Dual neutrophil subsets exacerbate or suppress inflammation in tuberculosis via IL-1β or PD-L1

IF 3.3 2区生物学 Q1 BIOLOGY

Life Science Alliance Pub Date : 2024-05-21 DOI:10.26508/lsa.202402623

Emilie Doz-Deblauwe, Badreddine Bounab, F. Carreras, J. Fahel, Sergio C. Oliveira, Mohamed Lamkanfi, Y. Le Vern, P. Germon, Julien Pichon, Florent Kempf, Christophe Paget, Aude Rémot, Nathalie Winter

引用次数: 0

Abstract

Neutrophils, key cells in tuberculosis, reach the lungs as two distinct subsets playing opposite roles in inflammation: either exacerbating via IL-1b or dampening via PD-L1.

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双中性粒细胞亚群通过 IL-1β 或 PD-L1 加重或抑制结核病的炎症反应

中性粒细胞是结核病的关键细胞，它们以两种不同的亚群形式进入肺部，在炎症中发挥着相反的作用：或者通过 IL-1b 使炎症加剧，或者通过 PD-L1 使炎症减弱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Life Science Alliance Agricultural and Biological Sciences-Plant Science

CiteScore

5.80

自引率

2.30%

发文量

241

审稿时长

10 weeks

期刊介绍： Life Science Alliance is a global, open-access, editorially independent, and peer-reviewed journal launched by an alliance of EMBO Press, Rockefeller University Press, and Cold Spring Harbor Laboratory Press. Life Science Alliance is committed to rapid, fair, and transparent publication of valuable research from across all areas in the life sciences.