Case report: CBD: THC medical cannabis in the treatment of neuropathic pain

Maria Teresa R J Jacob, Beatriz J J Milani
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Abstract

Chronic neuropathic pain affects millions of adults worldwide, creating a direct impact on quality of life. The control of neuropathic pain is a challenge in daily clinical practice. Current pharmacological treatment options for neuropathic pain afford substantial benefit for only a few people, often with adverse effects that outweigh the benefits. There is a need to explore other treatment options, with different mechanisms of action for treatment of this pathology. The use of cannabis and cannabinoid products is a growing area of research for the treatment of different pathologies including neuropathic pain. The studies developed so far and what is observed in the clinical practice, demonstrate the importance of this medication in a pathology of such complexity and difficult control, besides of that, more randomized controlled studies are needed to confirm medical cannabis an adjunct medication in the treatment of neuropathic pain. This case report aims to demonstrate the validity of joining GMP cannabis products as an adjuvant therapy for an effective with low profile side effects treatment leading to an improvement in quality of life.
病例报告:CBD:治疗神经性疼痛的四氢大麻酚医用大麻
慢性神经病理性疼痛影响着全球数百万成年人,直接影响他们的生活质量。控制神经病理性疼痛是日常临床实践中的一项挑战。目前针对神经病理性疼痛的药物治疗方案只能为少数人带来实质性的益处,其不良反应往往大于益处。有必要探索其他治疗方案,以不同的作用机制来治疗这种病症。使用大麻和大麻素产品治疗包括神经性疼痛在内的各种病症的研究领域日益扩大。迄今为止所开展的研究以及在临床实践中观察到的情况表明,这种药物对于如此复杂且难以控制的病症具有重要意义,除此之外,还需要更多的随机对照研究来证实医用大麻是治疗神经病理性疼痛的辅助药物。本病例报告旨在证明加入 GMP 大麻产品作为辅助疗法的有效性,该疗法有效且副作用小,可改善患者的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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