Lymphoblastic Lymphoma: Epidemio-Clinical, Therapeutic and Prognostic Aspects

N. Elhamdi, M. E. Baz, J. El Houdzi
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Abstract

Lymphoblastic lymphoma (LL) is a multifactorial, frequent and highly progressive but curable cancer, and one of the haemopathies frequently managed at the Mohammed VI University Hospital, Marrakech. Seventeen patients with lymphoblastic lymphoma (LL) were included in this study. The annual hospital incidence of LL in Marrakech was 1.8 cases/year. The 6-10 age group was in the majority (n=11; 70%). The sex ratio was 3.25 in favor of boys, and 82% had RAMED, which corresponds to a low socioeconomic level. Dyspnea was found in 10 patients (60%). Stage 3 was in the majority (n=7; 70%). Diagnosis was made by cytology in 94% of patients, histology in 23% and immunohistochemistry in 82%. Four patients died of chemotherapy toxicity after blood product rupture, and 3 of disease progression on chemotherapy. The 10 patients in remission survived event-free for an average of 21 months.
淋巴母细胞淋巴瘤:流行病学-临床、治疗和预后方面
淋巴母细胞淋巴瘤(LL)是一种多因素、多发、高度进展性但可治愈的癌症,也是马拉喀什穆罕默德六世大学医院经常治疗的血液病之一。本研究共纳入了 17 名淋巴细胞淋巴瘤(LL)患者。马拉喀什淋巴瘤的年住院发病率为 1.8 例/年。6-10岁年龄组占多数(11人;70%)。性别比为 3.25,男孩居多,82% 的患者患有 RAMED,这与较低的社会经济水平相对应。10名患者(60%)出现呼吸困难。大多数患者(7 人;70%)处于第 3 期。94%的患者通过细胞学诊断,23%通过组织学诊断,82%通过免疫组化诊断。4 名患者死于血制品破裂后的化疗毒性,3 名患者死于化疗后的疾病进展。10名病情缓解的患者平均存活了21个月。
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