Too Much of a Good Thing: Severe Hypercalcemia Presenting with Lethargy and Kidney Failure.

Q4 Medicine
Praxis Pub Date : 2024-04-01 DOI:10.23785/PRAXIS.2024.04.005
Patrick Hofmann, Arcangelo Friedrich Carta, Christian Trachsel, Birgit Maria Helmchen
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引用次数: 0

Abstract

Introduction: We present a case of a 58-year-old man with a history of laryngo-pharyngectomy including bilateral thyroidectomy due to hypopharyngeal cancer presenting with lethargy, acute kidney failure, and hypercalcemia. Milk alkali syndrome was diagnosed given the history of high-dose calcium / vitamin D supplementation after ruling out other causes of hypercalcemia. After initial treatment with normal saline, furosemide and denosumab, the patient developed severe symptomatic hypocalcemia as a rare adverse effect of denosumab.

好东西太多:严重高钙血症伴有嗜睡和肾衰竭。
导言:我们报告了一例 58 岁男性患者的病例,该患者曾因下咽癌接受过喉咽切除术(包括双侧甲状腺切除术),表现为嗜睡、急性肾衰竭和高钙血症。在排除了导致高钙血症的其他原因后,考虑到患者曾服用大剂量钙/维生素 D 补充剂,因此诊断为奶碱综合征。最初使用生理盐水、呋塞米和地诺单抗治疗后,患者出现了严重的症状性低钙血症,这是地诺单抗的罕见不良反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Praxis
Praxis Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
146
审稿时长
12 weeks
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