A method for determining groups in cumulative incidence curves in competing risk data

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-22 DOI:10.1002/bimj.202300084

Marta Sestelo, Luís Meira-Machado, Nora M. Villanueva, Javier Roca-Pardiñas

引用次数: 0

Abstract

The cumulative incidence function is the standard method for estimating the marginal probability of a given event in the presence of competing risks. One basic but important goal in the analysis of competing risk data is the comparison of these curves, for which limited literature exists. We proposed a new procedure that lets us not only test the equality of these curves but also group them if they are not equal. The proposed method allows determining the composition of the groups as well as an automatic selection of their number. Simulation studies show the good numerical behavior of the proposed methods for finite sample size. The applicability of the proposed method is illustrated using real data.

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在竞争风险数据的累积发病率曲线中确定组别的方法。

累积发生率函数是在存在竞争风险的情况下估算特定事件边际概率的标准方法。分析竞争风险数据的一个基本但重要的目标是比较这些曲线，但这方面的文献有限。我们提出了一种新的程序，不仅可以检验这些曲线是否相等，还可以在不相等的情况下对它们进行分组。所提出的方法可以确定组的组成，并自动选择组的数量。模拟研究表明，在样本数量有限的情况下，所提出的方法具有良好的数值表现。使用真实数据说明了所提方法的适用性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.