Research Advances in Vascular Remodeling in Choke Vessels of Perforator Flap: A Systematic Review.

IF 1.4 4区医学 Q3 SURGERY

Annals of Plastic Surgery Pub Date : 2024-08-01 Epub Date: 2024-05-22 DOI:10.1097/SAP.0000000000003980

Jiahao Ji, Dondli Chen, Jiamin Ni, Fei Chang

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引用次数: 0

Abstract

Background: As a significant bridge between perforasomes, choke vessels are the key structure of blood supply expansion, also a prerequisite for preventing distal ischemic necrosis of the multiterritory perforator flap, where the remodeling of choke vessels after flap elevation plays an essential role. This systematic review highlights the underlying mechanisms and clinical ways to promote remodeling of choke vessels, as well as experimental observation approaches to further guide researchers.

Methods: A systematic review was conducted from 1975 to 2023 through PubMed, EMBASE, Web of Science, and Cochrane database with the key words "choke vessels" and "perforator flap" to investigate the mechanisms and ways to promote remodeling of choke vessels as well as observation approaches. The inclusion criteria and exclusion criteria were set to screen the literature.

Results: A total of 94 literatures were obtained through database retrieval. After removing the duplicate literature, reading the title and abstract, and reviewing the full text finally, 33 articles were included in the final study.

Conclusions: The underlying remodeling of choke vessels may be related to fluid shear stress, hypoxia, and inflammation. The clinical ways to promote remodeling of choke vessels include surgical delay, arterial supercharge, venous superdrainage, drugs, and stem cells. Various experimental methods of observing microvascular morphology allow for a comprehensive research of choke vessels.

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穿孔瓣噎膈血管重塑的研究进展：系统性综述。

背景：作为穿孔器之间的重要桥梁，阻塞血管是血供扩张的关键结构，也是防止多孔皮瓣远端缺血坏死的前提，其中皮瓣提升后阻塞血管的重塑起着至关重要的作用。本系统性综述强调了促进噎管重塑的潜在机制和临床方法，以及实验观察方法，以进一步指导研究人员：方法：以 "噎管 "和 "穿孔器皮瓣 "为关键词，通过 PubMed、EMBASE、Web of Science 和 Cochrane 数据库对 1975 年至 2023 年期间的研究进行了系统综述，以探讨促进噎管重塑的机制、方式和观察方法。筛选文献时设定了纳入标准和排除标准：通过数据库检索共获得 94 篇文献。结果：通过数据库检索共获得 94 篇文献，在去除重复文献、阅读标题和摘要、审阅全文后，最终有 33 篇文章被纳入研究：结论：噎膈血管重塑的根本原因可能与流体剪切应力、缺氧和炎症有关。促进噎管血管重塑的临床方法包括手术延迟、动脉增压、静脉超引流、药物和干细胞。通过各种观察微血管形态的实验方法，可以对扼流圈血管进行全面研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Plastic Surgery 医学-外科

CiteScore

2.70

自引率

13.30%

发文量

584

审稿时长

6 months

期刊介绍： The only independent journal devoted to general plastic and reconstructive surgery, Annals of Plastic Surgery serves as a forum for current scientific and clinical advances in the field and a sounding board for ideas and perspectives on its future. The journal publishes peer-reviewed original articles, brief communications, case reports, and notes in all areas of interest to the practicing plastic surgeon. There are also historical and current reviews, descriptions of surgical technique, and lively editorials and letters to the editor.