Epigenetics comprehensive experimental course based on the integration of science and education to cultivate students' ability of cutting-edge innovation.

Q3 Medicine
遗传 Pub Date : 2023-12-20 DOI:10.16288/j.yczz.23-179
Xiu-Fang Ou, Ying Wu, Ning Li, Li-Li Jiang, Bao Liu, Lei Gong
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引用次数: 0

Abstract

The integration of science and education is an effective way for universities to cultivate students in cutting-edge innovative interests. Epigenetics is the expansion of classical genetics, the corresponding experimental courses of which have not been integrated into the current teaching system. In this paper, by taking advantage of our laboratory's research on the DNA methylation maintenance gene, OsMET1-2 in rice, we have integrated our innovative findings in the education curriculum, and built a comprehensive teaching system on experimentation research, which greatly stimulates the curiosity of the students. Taking the OsMET1-2 mutants and its isogenic wild-type rice plants as experimental materials, this course has successfully demonstrated a causal link between genetic mutation and epigenetic variation, a topic widely interested by the students in learning genetics and epigenetics. Through the practice of this course, students have a deeper understanding of the important role of epigenetic modifications, their scientific research capabilities have been greatly improved, thereby strongly supporting the cultivation of top innovative talents among the students.

表观遗传学综合实验课程立足于科教融合,培养学生前沿创新能力。
科教融合是高校培养学生前沿创新兴趣的有效途径。表观遗传学是经典遗传学的拓展,其相应的实验课程尚未纳入现行教学体系。本文利用本实验室对水稻DNA甲基化维持基因OsMET1-2的研究,将创新成果融入教学课程,构建了一套完整的实验研究性教学体系,极大地激发了学生的求知欲。本课程以OsMET1-2突变体及其同源野生型水稻植株为实验材料,成功证明了基因突变与表观遗传变异之间的因果关系,是学生学习遗传学和表观遗传学普遍感兴趣的课题。通过本课程的实践,学生对表观遗传修饰的重要作用有了更深刻的认识,科研能力得到了极大的提高,从而有力地支持了学生拔尖创新人才的培养。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
遗传
遗传 Medicine-Medicine (all)
CiteScore
2.50
自引率
0.00%
发文量
6699
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