[COVID-19 in the intensive care unit].

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-05-01 DOI:10.1055/a-1854-2693

André P Becker, Sebastian Mang, Torben M Rixecker, Philipp M Lepper

引用次数: 1

Abstract

The acute respiratory failure as well as ARDS (acute respiratory distress syndrome) have challenged clinicians since the initial description over 50 years ago. Various causes can lead to ARDS and therapeutic approaches for ARDS/ARF are limited to the support or replacement of organ functions and the prevention of therapy-induced consequences. In recent years, triggered by the SARS-CoV-2 pathogen, numerous cases of acute lung failure (C-ARDS) have emerged. The pathophysiological processes of classical ARDS and C-ARDS are essentially similar. In their final stages of inflammation, both lead to a disruption of the blood-air barrier. Treatment strategies for C-ARDS, like classical ARDS, focus on supporting or replacing organ functions and preventing consequential damage. This article summarizes the treatment strategies in the intensive care unit.

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[重症监护室中的 COVID-19]。

自 50 多年前首次描述急性呼吸衰竭和 ARDS（急性呼吸窘迫综合征）以来，它一直是临床医生面临的挑战。导致 ARDS 的原因多种多样，而 ARDS/ARF 的治疗方法仅限于支持或替代器官功能以及预防治疗引起的后果。近年来，由 SARS-CoV-2 病原体引发的急性肺不张（C-ARDS）病例层出不穷。传统 ARDS 和 C-ARDS 的病理生理过程基本相似。在炎症的最后阶段，两者都会导致血气屏障的破坏。与传统的 ARDS 一样，C-ARDS 的治疗策略也侧重于支持或替代器官功能以及预防相应的损伤。本文总结了重症监护病房的治疗策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.