Defining national research priorities for prostate cancer in Zambia: using the Delphi process for comprehensive cancer policy setting in sub-Saharan Africa

D. Lombe, M. Mwamba, M. Simwinga, Virginia Bond, A. Ssemata, R. Muhumuza, Janet Seeley, K. Lishimpi, Victor Mapulanga, John Kachimba, Ajay Aggarwal, S. Msadabwe
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Abstract

Locally led research on cancer is needed in sub-Saharan Africa to set feasible research priorities that inform national policy. The aim of this project was to develop a research agenda for national cancer control planning, using a nationally driven approach, focused on barriers to diagnosis and high-quality treatment for prostate cancer in Zambia.This was a Delphi process. 29 stakeholders were scored barriers on feasibility, the proportion of patients affected, the impact on patient outcomes and if there was a potential to address health systems barriers meaningfully. There were three rounds (R) to the process: (R1 and R2) by electronic survey and (R3) in-person meeting. In R1 statements scoring above 15 from over 70% of participants were prioritised immediately for R3 discussion. Those scoring below 30% were dropped and those in between were re-surveyed in R2.22 and 17 of the 29 stakeholders responded to R1 and R2. 14 stakeholders attended R3. National priority research areas for prostate cancer in Zambia were identified as prostate cancer awareness; building affordable high-quality diagnostic capacity; affordability of specialist cancer treatments; supporting better access to medicines; delivery and coordination of services across the pathway and staff training.The suggested seven priority areas allow for the development of the prostate cancer control programme to be conducted in a holistic manner. The expectation is with this guidance international partners can contribute within the frameworks of the local agenda for sustainable development to be realised.
确定赞比亚前列腺癌的国家研究重点:在撒哈拉以南非洲利用德尔菲进程制定全面的癌症政策
撒哈拉以南非洲地区需要地方主导的癌症研究,以确定可行的研究重点,为国家政策提供依据。该项目的目的是为国家癌症控制规划制定研究议程,采用国家驱动的方法,重点关注赞比亚前列腺癌诊断和高质量治疗的障碍。29 个利益相关者根据可行性、受影响患者的比例、对患者疗效的影响以及是否有可能有意义地解决卫生系统障碍等因素对障碍进行评分。该过程分为三轮(R):(R1 和 R2)电子调查和(R3)面对面会议。在 R1 中,超过 70% 的参与者的发言得分超过 15 分,这些发言将被立即列为 R3 讨论的优先事项。在 R1 和 R2 中,29 位利益相关者中有 17 位做出了回应。14 位利益相关者参加了 R3 讨论。赞比亚前列腺癌的国家优先研究领域被确定为:前列腺癌意识;建立负担得起的高质量诊断能力;负担得起的专科癌症治疗;支持更好地获取药物;提供和协调整个治疗路径的服务以及员工培训。我们希望国际合作伙伴能够在此指导下,在当地可持续发展议程的框架内做出贡献。
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