Ethnopharmacology, phytochemistry, pharmacology and product application of Platycodon grandiflorum: A review

IF 4.7 4区医学 Q1 CHEMISTRY, MEDICINAL

Chinese Herbal Medicines Pub Date : 2024-07-01 DOI:10.1016/j.chmed.2024.01.005

Lanying Zhang , Xinrui Wang , Jingze Zhang , Dailin Liu , Gang Bai

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引用次数: 0

Abstract

Platycodonis Radix (Jiegeng in Chinese) is a well-known traditional Chinese medicine used for both medicinal and culinary purposes. Its historical use as an antitussive and expectorant has been extensively documented. Researchers, to date, have identified 219 chemical constituents in Platycodon grandiflorum (Jacq.) A. DC, encompassing 89 saponins, 11 flavonoids, 21 polysaccharides, 14 phenolic acids, six polyacetylenes, five sterols, 34 fatty acids, 17 amino acids, and 22 trace elements. Jiegeng exhibits diverse pharmacological effects, including antitussive and anti-phlegm properties, anti-cancer activity, anti-inflammatory effects, immune regulation, antioxidant properties, anti-obesity, and antidiabetic effects. Additionally, Jiegeng shows potential in protecting the heart and liver. Beyond its medicinal benefits, Jiegeng is highly esteemed in culinary applications, and its global demand is on the rise. Its utilization has expanded beyond medicine and food to encompass daily necessities, cosmetics, agricultural supplies, and other fields. Currently, there are 18 272 patents related to P. grandiflorum. This comprehensive review summarizes the latest research published over the past 20 years, providing a robust foundation for further exploration of the medicinal and health benefits of P. grandiflorum.

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桔梗的民族药理学、植物化学、药理学和产品应用：综述

桔梗是一种著名的药食两用传统中药。桔梗作为止咳药和祛痰药的历史已被广泛记载。迄今为止，研究人员已从桔梗中鉴定出 219 种化学成分，包括 89 种皂苷、11 种黄酮、21 种多糖、14 种酚酸、6 种多炔基、5 种甾醇、34 种脂肪酸、17 种氨基酸和 22 种微量元素。鸡血藤具有多种药理作用，包括止咳化痰、抗癌、抗炎、免疫调节、抗氧化、抗肥胖和抗糖尿病作用。此外，鸡血藤还具有保护心脏和肝脏的潜力。除了药用功效外，鸡血藤在烹饪方面的应用也备受推崇，全球对它的需求也在不断增加。其用途已从医药和食品扩展到日用品、化妆品、农业用品和其他领域。目前，有 18 272 项专利与大叶女贞有关。本综述总结了过去 20 年发表的最新研究成果，为进一步探索大花金银花的药用和保健功效奠定了坚实的基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chinese Herbal Medicines CHEMISTRY, MEDICINAL-

CiteScore

4.40

自引率

5.30%

发文量

629

审稿时长

10 weeks

期刊介绍： Chinese Herbal Medicines is intended to disseminate the latest developments and research progress in traditional and herbal medical sciences to researchers, practitioners, academics and administrators worldwide in the field of traditional and herbal medicines. The journal's international coverage ensures that research and progress from all regions of the world are widely included. CHM is a core journal of Chinese science and technology. The journal entered into the ESCI database in 2017, and then was included in PMC, Scopus and other important international search systems. In 2019, CHM was successfully selected for the “China Science and Technology Journal Excellence Action Plan” project, which has markedly improved its international influence and industry popularity. CHM obtained the first impact factor of 3.8 in Journal Citation Reports (JCR) in 2023.