Atypical Giant Parathyroid Adenoma, Case Report

K. Helael, A. Y. Mheidat, Mohammad Harbi Odat, Hudaib Nabeel Swalha, Anas Horani, Ra’ad Ahmad Al-omari, Mansour Mohanmmad Abushqair, Mohammad Ahmad Abu-Aloush, Mohammad Hamdi Ahmad Alhyari, Mut’az Jawher Alwadi, Yazan Mohammad Ahmad Al Momani, Habeeb lutfi Etewi
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Abstract

Atypical giant parathyroid adenoma is a rare tumor with unusual histological features, an unusual presentation of primary hyperparathyroidism but more elevated laboratory findings and more severe clinical presentation due to larger tissue mass, and defined as weighing>3.5 g, leading to diagnostic and therapeutic challenges. Herein, we report a case of a 56-year-old woman who presented with a palpable neck mass, fatigue, persistent hypercalcemia, osteoporosis and asymptomatic renal stones, Ultrasound showed a left-sided solid nodule, and Sestamibi nuclear scan showed a giant parathyroid adenoma. The diagnosis of giant atypical parathyroid adenoma was confirmed after surgical excision size (3.5*1.5cm). We discuss the investigations, treatment, and outcome of this rare case and highlight the importance of long-term follow-up care.
非典型巨大甲状旁腺腺瘤,病例报告
非典型巨大甲状旁腺腺瘤是一种罕见的肿瘤,具有不寻常的组织学特征,是原发性甲状旁腺功能亢进症的一种不寻常表现,但由于组织肿块较大,实验室检查结果升高,临床表现更为严重,其定义为重量大于3.5克,给诊断和治疗带来了挑战。超声检查显示左侧实性结节,Sestamibi核素扫描显示巨大甲状旁腺腺瘤。手术切除后(3.5*1.5厘米),确诊为巨大非典型甲状旁腺腺瘤。我们讨论了这一罕见病例的检查、治疗和结果,并强调了长期随访的重要性。
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