Comparative analysis of serum titanium level in patient with healthy dental implant and patients with peri-implantitis- A cross sectional prospective study

Abstract

Objectives: Titanium dental implants can last for more than two decades in the oral environment. Corrosion of the implant surface can release metallic particles or ions into surrounding tissue. The metallic constituents like titanium in human blood serum have not been fully studied. The study compares titanium serum levels before and after dental implant placement and compares levels in patients with healthy implants and those with per-implantitis. Methods: The study comprised 2groups of Group 1 patient observing implant surgery and group 2 patients with diagnosed peri-implantitis. Each group comprised of 60 patients. Serum titanium level was measured from blood obtained from Group 1 at three different intervals (one month prior to implant surgery, 4th and 8th month after successful loading) and from Group 2 during the course of peri-implantitis by inductively coupled plasma–mass spectroscopy. The statistical analysis was done for the obtained data. Results: Analysis showed a raised level of serum titanium at 4th month of post implant placement (2.39 mg/dl) and in patient with peri-implantitis(2.94 mg/dl) and both levels are significantly differ (ANOVA test) from pre-surgical estimation of serum titanium level (1.79 mg/dl). Conclusions: Understanding the correlation between titanium corrosion and peri-implantitis is vital for enhancing the long-term success and safety of dental implants. Additional research is required to investigate these links and potential strategies to protect the well-being of implant patients.