Beyond PI-RADS: Combining MRI PI-RADS and PSMA-PET/CT PRIMARY Score in a Composite (P) Score for More Accurate Diagnosis of Clinically Significant Prostate Cancer.
Louise Emmett, Nathan Papa, Thomas A Hope, Wolfgang Fendler, Jeremie Calais, Irene Burger, Matthias Eiber, Francesco Barbato, Daniel Moon, William Counter, Nikeith John, Alan Xue, Anthony Franklin, James Thompson, Kris Rasiah, Mark Frydenberg, John Yaxley, James Buteau, Shikha Agrawal, Bao Ho, Andrew Nguyen, Victor Liu, Jonathan Lee, Henry Woo, Edward Hsiao, Thomas Sutherland, Elyse Perry, Phillip Stricker, Michael S Hofman, Veeru Kasivisvanathan, Matthew Roberts, Declan Murphy
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Abstract
The PI-RADS score is standard of care for clinically significant prostate cancer (csPCa) diagnosis. The PRIMARY-score (PSMA-PET/CT) also has high diagnostic accuracy for csPCa. This study aimed to develop an easily calculated combined (P) score for csPCa detection (ISUP ≥ 2) incorporating separately read PI-RADS and PRIMARY scores, with external validation.
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