Early survival in Atlantic salmon is associated with parental genotypes at loci linked to timing of maturation.

IF 3.1 2区 环境科学与生态学 Q2 ECOLOGY
Evolution Pub Date : 2024-07-29 DOI:10.1093/evolut/qpae072
Tutku Aykanat, Darryl McLennan, Neil B Metcalfe, Jenni M Prokkola
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引用次数: 0

Abstract

Large effect loci often contain genes with critical developmental functions and potentially broad effects across life stages. However, their life stage-specific fitness consequences are rarely explored. In Atlantic salmon, variation in two large-effect loci, six6 and vgll3, is linked to age at maturity and several physiological and behavioral traits in early life. By genotyping the progeny of wild Atlantic salmon that were planted into natural streams with nutrient manipulations, we tested if genetic variation in these loci is associated with survival in early life. We found that higher early-life survival was linked to the genotype associated with late maturation in the vgll3, but with early maturation in the six6 locus. These effects were significant in high nutrients but not in low-nutrient streams. The differences in early survival were not explained by additive genetic effects in the offspring generation but by maternal genotypes in the six6 locus and by both parents' genotypes in the vgll3 locus. Our results suggest that indirect genetic effects of large-effect loci can be significant determinants of offspring fitness. This study demonstrates an intriguing case of how large-effect loci can exhibit complex fitness associations across life stages in the wild and indicates that predicting evolutionary dynamics is difficult.

大西洋鲑鱼的早期存活与父母基因型中与成熟时间有关的基因位点有关。
大效应基因座通常包含具有关键发育功能的基因,这些基因可能对整个生命阶段产生广泛影响。然而,对生命阶段特异性适存后果的研究却很少。在大西洋鲑鱼中,两个大效应位点 six6 和 vgll3 的变异与成熟年龄以及生命早期的一些生理和行为特征有关。通过对野生大西洋鲑的后代进行基因分型,我们测试了这些基因位点的遗传变异是否与生命早期的存活率有关。我们发现,较高的早期存活率与 vgll3 基因位点的晚熟基因型有关,但与 six6 基因位点的早熟基因型有关。这些影响在高营养溪流中显著,但在低营养溪流中不显著。早熟存活率的差异不是由子代中的加性遗传效应解释的,而是由母体在 six6 基因座上的基因型和父母双方在 vgll3 基因座上的基因型解释的。我们的研究结果表明,大效应位点的间接遗传效应可能是决定子代健康状况的重要因素。这项研究展示了一个有趣的案例,说明大效应基因座如何在野外各生命阶段表现出复杂的适应性关联,并表明预测进化动态是困难的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Evolution
Evolution 环境科学-进化生物学
CiteScore
5.00
自引率
9.10%
发文量
0
审稿时长
3-6 weeks
期刊介绍: Evolution, published for the Society for the Study of Evolution, is the premier publication devoted to the study of organic evolution and the integration of the various fields of science concerned with evolution. The journal presents significant and original results that extend our understanding of evolutionary phenomena and processes.
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