The Profuse Bleeding Potential of Orbital Epithelioid Hemangioendotheliomas.

IF 1.2 4区 医学 Q3 OPHTHALMOLOGY
Ziad Jassar, Randa Al Barazi, Roula Hourany, Ramzi Alameddine
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引用次数: 0

Abstract

Epithelioid hemangioendothelioma is a rare vascular tumor originating from vascular endothelial or pre-endothelial cells. We present the case of a 4-month-old male with a rapidly enlarging left zygomatico-orbital tumor causing mass effect on the eye globe. Examination revealed a large, nontender, solid lesion. CT angiography showed no major feeder or intralesional vessels. Complete surgical excision was performed, which was complicated by life-threatening intraoperative bleeding and successfully controlled with electrocautery. Microscopically, tumor cells exhibited varying morphologies. Immunohistochemistry confirmed the diagnosis of epithelioid hemangioendothelioma (positive for CD31 and CD34, negative for CK AE1/AE3). We also highlight 2 similar case reports with life-threatening bleeding complications. Surgeons should be aware of this condition and optimize surgical preparation, including blood products, to manage potential bleeding complications.

眼眶上皮样血管内皮细胞瘤的大量出血潜能。
上皮样血管内皮细胞瘤是一种罕见的血管肿瘤,起源于血管内皮细胞或前内皮细胞。本病例是一名 4 个月大的男性,左侧颧眶肿瘤迅速增大,导致眼球肿块。检查发现该肿瘤为巨大、无触痛、实性病变。CT 血管造影显示没有主要的供养血管或内部血管。手术进行了全切,术中出血危及生命,电烧成功控制了出血。显微镜下,肿瘤细胞形态各异。免疫组化确诊为上皮样血管内皮细胞瘤(CD31 和 CD34 阳性,CK AE1/AE3 阴性)。我们还重点介绍了两例类似的病例报告,其出血并发症危及生命。外科医生应了解这种情况,并优化手术准备,包括血制品,以控制潜在的出血并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.50
自引率
10.00%
发文量
322
审稿时长
3-8 weeks
期刊介绍: Ophthalmic Plastic and Reconstructive Surgery features original articles and reviews on topics such as ptosis, eyelid reconstruction, orbital diagnosis and surgery, lacrimal problems, and eyelid malposition. Update reports on diagnostic techniques, surgical equipment and instrumentation, and medical therapies are included, as well as detailed analyses of recent research findings and their clinical applications.
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