Ishita Mostafa, Matthew C. Hibberd, Steven J. Hartman, Md Hasan Hafizur Rahman, Mustafa Mahfuz, S. M. Tafsir Hasan, Per Ashorn, Michael J. Barratt, Tahmeed Ahmed, Jeffrey I. Gordon
{"title":"A microbiota-directed complementary food intervention in 12-18-month-old Bangladeshi children improves linear growth","authors":"Ishita Mostafa, Matthew C. Hibberd, Steven J. Hartman, Md Hasan Hafizur Rahman, Mustafa Mahfuz, S. M. Tafsir Hasan, Per Ashorn, Michael J. Barratt, Tahmeed Ahmed, Jeffrey I. Gordon","doi":"10.1101/2024.04.29.24306564","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Globally, stunting affects ∼150 million children under five, while wasting affects nearly 50 million. Current interventions have had limited effectiveness in ameliorating long-term sequelae of undernutrition including stunting, cognitive deficits and immune dysfunction. Disrupted development of the gut microbiota has been linked to the pathogenesis of undernutrition, providing potentially new treatment approaches.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"19 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Nutrition","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.04.29.24306564","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background Globally, stunting affects ∼150 million children under five, while wasting affects nearly 50 million. Current interventions have had limited effectiveness in ameliorating long-term sequelae of undernutrition including stunting, cognitive deficits and immune dysfunction. Disrupted development of the gut microbiota has been linked to the pathogenesis of undernutrition, providing potentially new treatment approaches.