Maximal Aerobic Power, Quality of Life, and Ejection Fraction in Survivors of Childhood Cancer Treated with Anthracyclines.

IF 1.4 4区 医学 Q3 PEDIATRICS
Maritza Martínez Tagle, Pavel Loeza Magaña, Alma Edith Benito Reséndiz, Iliana Lucatero Lecona, Farina Esther Arreguín González, Alberto Chávez Delgado
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引用次数: 0

Abstract

Background: Anthracycline-induced cardiotoxicity is a frequent complication that can occur at any stage of treatment, even in survivors.

Objective: To determine maximum aerobic power, quality of life, and left ventricular ejection fraction in childhood cancer survivors treated with anthracyclines.

Design: Cross-sectional, observational study.

Methods: The left ventricular ejection fraction was obtained from the transthoracic echocardiogram report in the medical records. Each patient underwent a 6-minute walk test, assessment of maximum aerobic power on a cycle ergometer, and evaluation of perceived exertion using the EPInfant scale, and finally, their quality of life was evaluated using the pediatric quality of life inventory model.

Results: A total of 12 patients were studied, with an average of 16.2 years of age. All patients exhibited a left ventricular ejection fraction >60%, the mean distance covered in the 6-minute walk test was 516.7 m, and the mean of the maximum aerobic power was 70 W. Low quality of life scores were obtained in the physical and psychosocial aspects. In the Pearson test, a weak correlation without statistical significance was found between all the variables studied.

Conclusions: Simultaneously with the detection of cardiotoxicity in childhood cancer survivors, it is pertinent to perform physical evaluations as physical condition and cardiotoxicity seem to be issues that are not necessarily dependent.

接受蒽环类药物治疗的儿童癌症幸存者的最大有氧运动能力、生活质量和射血分数。
背景:蒽环类药物引起的心脏毒性是一种常见的并发症,可发生在治疗的任何阶段,甚至是幸存者:目的:确定接受蒽环类药物治疗的儿童癌症幸存者的最大有氧运动能力、生活质量和左心室射血分数:设计:横断面观察研究:从病历中的经胸超声心动图报告中获取左心室射血分数。每位患者都接受了 6 分钟步行测试、在自行车测力计上评估最大有氧功率、使用 EPInfant 量表评估体力消耗,最后使用儿科生活质量清单模型评估他们的生活质量:共有 12 名患者接受了研究,平均年龄为 16.2 岁。所有患者的左心室射血分数均大于 60%,6 分钟步行测试的平均距离为 516.7 米,最大有氧功率的平均值为 70 瓦。在皮尔逊测试中,所有研究变量之间都存在微弱的相关性,但无统计学意义:结论:在检测儿童癌症幸存者心脏毒性的同时,进行身体评估也很重要,因为身体状况和心脏毒性似乎是不一定相关的问题。
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来源期刊
Pediatric Exercise Science
Pediatric Exercise Science 医学-生理学
CiteScore
2.80
自引率
0.00%
发文量
33
审稿时长
>12 weeks
期刊介绍: Pediatric Exercise Science is a journal committed to enriching the scientific knowledge of exercise during childhood and adolescence. To this end it publishes information that contributes to an understanding of (a) the unique aspects of the physiologic, physical, biochemical, and psychologic responses of children to exercise, (b) the role of exercise in the treatment of pediatric chronic diseases, (c) the importance of physical activity in the prevention of illness and preservation of wellness, and (d) the means by which participation in sports may be made safer and more enjoyable for children and youth. Consideration will be given for publication of work by various methodologies consistent with the scientific approach. Besides original research, the journal includes review articles, abstracts from other journals, book reviews, and editorial comments. Pediatric Exercise Science encourages the expression of conflicting opinions regarding children and exercise by providing a forum for alternative viewpoints. At the same time it serves as a means of accumulating a base of research information that will allow application of experimental data to clinical practice. The scientific disciplines contributing to this body of knowledge are diverse. Therefore it is the purpose of this journal to provide a common focus for disseminating advances in the science of exercise during childhood. In doing so, the journal allows the opportunity for cross-fertilization of ideas between disciplines that will potentiate the growth of knowledge in this field. Pediatric Exercise Science seeks to stimulate new ideas regarding exercise in children and to increase the awareness of scientists, health care providers, and physical educators of the importance of exercise during childhood.
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