Intranasal etripamil for rapid treatment of paroxysmal supraventricular tachycardia.

IF 1.6 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS
Future cardiology Pub Date : 2024-01-01 Epub Date: 2024-05-20 DOI:10.1080/14796678.2024.2342651
Peter Calvert, Dhiraj Gupta
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引用次数: 0

Abstract

Paroxysmal supraventricular tachycardia (PSVT) is a common arrhythmia that, although usually benign, can occur unpredictably, cause disabling symptoms and significantly impair quality of life. If spontaneous resolution does not occur, the only current self-treatment is for the patient to attempt vagal maneuvers, however, these are frequently unsuccessful. Hospital attendance is then required for intravenous therapy. Etripamil, an intranasal calcium channel blocker similar to verapamil, may be able to fill this therapeutic gap, allowing rapid self-treatment of PSVT at home. This narrative review discusses the latest evidence for etripamil and its potential role in future clinical practice.

鼻内注射依曲帕米快速治疗阵发性室上性心动过速。
阵发性室上性心动过速(PSVT)是一种常见的心律失常,虽然通常是良性的,但会不可预知地发生,引起致残症状,严重影响生活质量。如果不能自发缓解,目前唯一的自我治疗方法是让患者尝试迷走神经操作,但这些操作往往不成功。这时就需要到医院进行静脉注射治疗。与维拉帕米相似的鼻内钙通道阻滞剂依曲帕米或许能填补这一治疗空白,使患者能在家中快速自我治疗 PSVT。本综述讨论了依曲帕米的最新证据及其在未来临床实践中的潜在作用。
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来源期刊
Future cardiology
Future cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.80
自引率
5.90%
发文量
87
期刊介绍: Research advances have contributed to improved outcomes across all specialties, but the rate of advancement in cardiology has been exceptional. Concurrently, the population of patients with cardiac conditions continues to grow and greater public awareness has increased patients" expectations of new drugs and devices. Future Cardiology (ISSN 1479-6678) reflects this new era of cardiology and highlights the new molecular approach to advancing cardiovascular therapy. Coverage will also reflect the major technological advances in bioengineering in cardiology in terms of advanced and robust devices, miniaturization, imaging, system modeling and information management issues.
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