Affinity alone does not drive long-lived plasma cell differentiation

IF 3.2 4区医学 Q3 CELL BIOLOGY

Immunology & Cell Biology Pub Date : 2024-05-07 DOI:10.1111/imcb.12770

Courtney E McDougal, Marion Pepper

引用次数: 0

Abstract

Long-lived plasma cells are important for preventing infection by maintaining baseline antibody titers. However, the cues leading to plasma cell differentiation remain unclear. In this article, we discuss recent work assessing the role of affinity on plasma cell differentiation.

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亲和力本身并不能驱动长寿命浆细胞分化。

长寿命浆细胞对于通过维持抗体滴度基线来预防感染非常重要。然而，导致浆细胞分化的线索仍不清楚。在这篇文章中，我们讨论了最近评估亲和力对浆细胞分化作用的工作。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Immunology & Cell Biology 医学-免疫学

CiteScore

7.50

自引率

2.50%

发文量

审稿时长

4-8 weeks

期刊介绍： The Australasian Society for Immunology Incorporated (ASI) was created by the amalgamation in 1991 of the Australian Society for Immunology, formed in 1970, and the New Zealand Society for Immunology, formed in 1975. The aim of the Society is to encourage and support the discipline of immunology in the Australasian region. It is a broadly based Society, embracing clinical and experimental, cellular and molecular immunology in humans and animals. The Society provides a network for the exchange of information and for collaboration within Australia, New Zealand and overseas. ASI members have been prominent in advancing biological and medical research worldwide. We seek to encourage the study of immunology in Australia and New Zealand and are active in introducing young scientists to the discipline.