Potential Applications of Blautia wexlerae in the Regulation of Host Metabolism.

IF 4.4 2区 生物学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Probiotics and Antimicrobial Proteins Pub Date : 2024-10-01 Epub Date: 2024-05-04 DOI:10.1007/s12602-024-10274-8
Wen Rui, Xiaoqian Li, Lijun Wang, Xuna Tang, Jingpeng Yang
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引用次数: 0

Abstract

Blautia wexlerae (B. wexlerae) is a strong candidate with the potential to become a next-generation probiotics (NGPs) and has recently been shown for the first time to exhibit potential in modulating host metabolic levels and alleviating metabolic diseases. However, the factors affecting the change in abundance of B. wexlerae and the pattern of its abundance change in the associated indications remain to be further investigated. Here, we summarize information from published studies related to B. wexlerae; analyze the effects of food source factors such as prebiotics, probiotics, low protein foods, polyphenols, vitamins, and other factors on the abundance of B. wexlerae; and explore the patterns of changes in the abundance of B. wexlerae in metabolic diseases, neurological diseases, and other diseases. At the same time, the development potential of B. wexlerae was evaluated in the direction of functional foods and special medical foods.

Abstract Image

Blautia wexlerae 在调节宿主代谢中的潜在应用。
Blautia wexlerae(B. wexlerae)是一种有潜力成为下一代益生菌(NGPs)的强大候选者,最近首次被证明具有调节宿主代谢水平和缓解代谢性疾病的潜力。然而,影响 B. wexlerae 丰度变化的因素及其在相关适应症中的丰度变化模式仍有待进一步研究。在此,我们总结了已发表的与 B. wexlerae 相关的研究信息,分析了益生元、益生菌、低蛋白食物、多酚、维生素等食物来源因素对 B. wexlerae 丰度的影响,并探讨了 B. wexlerae 在代谢性疾病、神经系统疾病和其他疾病中的丰度变化规律。同时,还评估了 B. wexlerae 在功能性食品和特殊医学食品方向的发展潜力。
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来源期刊
Probiotics and Antimicrobial Proteins
Probiotics and Antimicrobial Proteins BIOTECHNOLOGY & APPLIED MICROBIOLOGYMICROB-MICROBIOLOGY
CiteScore
11.30
自引率
6.10%
发文量
140
期刊介绍: Probiotics and Antimicrobial Proteins publishes reviews, original articles, letters and short notes and technical/methodological communications aimed at advancing fundamental knowledge and exploration of the applications of probiotics, natural antimicrobial proteins and their derivatives in biomedical, agricultural, veterinary, food, and cosmetic products. The Journal welcomes fundamental research articles and reports on applications of these microorganisms and substances, and encourages structural studies and studies that correlate the structure and functional properties of antimicrobial proteins.
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