Outcome Measures in Adult Vulvar Lichen Sclerosus: A Systematic Review.

IF 2.4 4区 医学 Q2 OBSTETRICS & GYNECOLOGY
Journal of Lower Genital Tract Disease Pub Date : 2024-07-01 Epub Date: 2024-05-07 DOI:10.1097/LGT.0000000000000819
Beth Morrel, Marianne J Ten Kate-Booij, Charlotte van Dijk, Wichor M Bramer, Curt W Burger, Suzanne G M A Pasmans, Irene A M van der Avoort
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引用次数: 0

Abstract

Objectives: Core outcome domains (CODs) for treatment of adult vulvar lichen sclerosus (VLS) have recently been established through a Delphi study. A number of measuring tools are available for evaluating VLS. The aim of this study is to identify available standardized measurement tools for the major CODs for VLS that have recently been defined, namely, physical findings and quality of life (QoL) specific to VLS.

Materials and methods: A systematic search through September 8, 2023, for measuring tools applicable to VLS regarding physical findings and QoL including sexual function or sexual well-being and self-image was performed.

Results: Thirty-five studies were included in the systematic review describing 26 tools covering the following 6 outcome domains: QoL-general health, QoL-lichen sclerosus specific, symptoms, clinical signs, emotional impact, and sexual functioning.

Conclusions: In current research, there is no uniformity in use of measurement tools for evaluating VLS. The established CODs to evaluate treatment of VLS are applicable for evaluating disease course as well. A comprehensive study to reach consensus regarding measurement of physical findings, QoL-lichen sclerosus specific, sexuality, and self-image taking the predetermined CODs and other factors such as age into account is needed.

成人外阴硬皮病的疗效测量:系统综述
目的:通过德尔菲研究,最近确定了成人外阴硬皮病(VLS)治疗的核心结果域(CODs)。目前有许多测量工具可用于评估 VLS。本研究的目的是针对最近确定的 VLS 主要 COD(即 VLS 特有的身体检查结果和生活质量(QoL))确定可用的标准化测量工具:截至 2023 年 9 月 8 日,对适用于 VLS 的身体检查结果和 QoL(包括性功能或性健康和自我形象)的测量工具进行了系统检索:结果:35 项研究被纳入系统综述,这些研究描述了 26 种工具,涵盖以下 6 个结果领域:结果:系统性综述中纳入了 35 项研究,描述了 26 种工具,涵盖以下 6 个结果域:QoL-一般健康、QoL-硬皮病特异性、症状、临床体征、情绪影响和性功能:在目前的研究中,用于评估 VLS 的测量工具并不统一。用于评估 VLS 治疗的既定 COD 也适用于评估病程。有必要开展一项综合研究,在考虑预定的标准判定和年龄等其他因素的基础上,就身体检查结果、QoL--硬皮病特异性、性功能和自我形象的测量达成共识。
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来源期刊
Journal of Lower Genital Tract Disease
Journal of Lower Genital Tract Disease OBSTETRICS & GYNECOLOGY-
CiteScore
6.80
自引率
8.10%
发文量
158
审稿时长
6-12 weeks
期刊介绍: The Journal of Lower Genital Tract Disease is the source for the latest science about benign and malignant conditions of the cervix, vagina, vulva, and anus. The Journal publishes peer-reviewed original research original research that addresses prevalence, causes, mechanisms, diagnosis, course, treatment, and prevention of lower genital tract disease. We publish clinical guidelines, position papers, cost-effectiveness analyses, narrative reviews, and systematic reviews, including meta-analyses. We also publish papers about research and reporting methods, opinions about controversial medical issues. Of particular note, we encourage material in any of the above mentioned categories that is related to improving patient care, avoiding medical errors, and comparative effectiveness research. We encourage publication of evidence-based guidelines, diagnostic and therapeutic algorithms, and decision aids. Original research and reviews may be sub-classified according to topic: cervix and HPV, vulva and vagina, perianal and anal, basic science, and education and learning. The scope and readership of the journal extend to several disciplines: gynecology, internal medicine, family practice, dermatology, physical therapy, pathology, sociology, psychology, anthropology, sex therapy, and pharmacology. The Journal of Lower Genital Tract Disease highlights needs for future research, and enhances health care. The Journal of Lower Genital Tract Disease is the official journal of the American Society for Colposcopy and Cervical Pathology, the International Society for the Study of Vulvovaginal Disease, and the International Federation of Cervical Pathology and Colposcopy, and sponsored by the Australian Society for Colposcopy and Cervical Pathology and the Society of Canadian Colposcopists.
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