Impact of current and previous sperm findings on outcomes of intrauterine insemination.

IF 2.7 3区医学 Q2 OBSTETRICS & GYNECOLOGY

Reproductive Medicine and Biology Pub Date : 2024-04-08 eCollection Date: 2024-01-01 DOI:10.1002/rmb2.12574

Maki Taniguchi, Haruhiko Kanasaki, Aki Oride, Hiroe Okada, Kayo Imamura, Satoru Kyo

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引用次数: 0

Abstract

Purpose: To examine the association between semen characteristics and outcomes of intrauterine insemination (IUI).

Methods: This retrospective analysis examined 1380 IUI procedures involving 421 couples. The association of clinical pregnancy with pre- and post-wash sperm characteristics was assessed.

Results: Pre- and post-wash sperm characteristics did not differ between IUI cycles that resulted in pregnancy and those that did not. When the motility of pre-wash sperm was below the normal range (<42%) established by the World Health Organization (WHO), the pregnancy rate was significantly lower. In the IUI cycles when post-wash sperm motility was below the WHO standard, pregnancy was not achieved. The frequency of improvement in post-wash sperm motility in repeated IUI cycles appeared to correlate with the success of future IUI cycles. At the fourth IUI cycle, pregnancy was not achieved unless the post-wash sperm motility was normal in at least two of three attempts. When post-wash sperm concentration was below the normal range, the woman's age did not affect the IUI outcomes.

Conclusions: Sperm motility above the lower limit of the WHO criteria in post-wash semen samples is an important factor in IUI outcomes.

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当前和以往的精子检测结果对宫腔内人工授精结果的影响。

目的：研究精液特征与宫腔内人工授精（IUI）结果之间的关系：这项回顾性分析研究了1380例宫腔内人工授精手术，涉及421对夫妇。评估了临床妊娠与清洗前后精子特征的关系：结果：导致妊娠的人工授精周期与未导致妊娠的人工授精周期的洗前和洗后精子特征没有差异。当清洗前精子的活力低于正常范围时（结论：精子活力高于正常范围的精子不会怀孕），清洗后精子的活力低于正常范围的精子不会怀孕：清洗后精液样本中精子活力高于世界卫生组织标准下限是影响人工授精结果的一个重要因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reproductive Medicine and Biology Multiple-

CiteScore

5.70

自引率

5.90%

发文量

审稿时长

20 weeks

期刊介绍： Reproductive Medicine and Biology (RMB) is the official English journal of the Japan Society for Reproductive Medicine, the Japan Society of Fertilization and Implantation, the Japan Society of Andrology, and publishes original research articles that report new findings or concepts in all aspects of reproductive phenomena in all kinds of mammals. Papers in any of the following fields will be considered: andrology, endocrinology, oncology, immunology, genetics, function of gonads and genital tracts, erectile dysfunction, gametogenesis, function of accessory sex organs, fertilization, embryogenesis, embryo manipulation, pregnancy, implantation, ontogenesis, infectious disease, contraception, etc.