Antibody association in solution: cluster distributions and mechanisms

IF 5.6 2区医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

mAbs Pub Date : 2024-04-26 DOI:10.1080/19420862.2024.2339582

Sandi Brudar, Leonid Breydo, Elisha Chung, Ken A. Dill, Nasim Ehterami, Ketan Phadnis, Samir Senapati, Mohammed Shameem, Xiaolin Tang, Muhammmad Tayyab, Barbara Hribar-Lee

引用次数: 0

Abstract

Understanding factors that affect the clustering and association of antibodies molecules in solution is critical to their development as therapeutics. For 19 different monoclonal antibody (mAb) sol...

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溶液中的抗体关联：集群分布与机制

了解影响抗体分子在溶液中聚集和结合的因素对于将它们开发成治疗药物至关重要。针对 19 种不同的单克隆抗体（mAb）溶液，我们提出了一种新的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

mAbs 工程技术-仪器仪表

CiteScore

10.70

自引率

11.30%

发文量

审稿时长

6-12 weeks

期刊介绍： mAbs is a multi-disciplinary journal dedicated to the art and science of antibody research and development. The journal has a strong scientific and medical focus, but also strives to serve a broader readership. The articles are thus of interest to scientists, clinical researchers, and physicians, as well as the wider mAb community, including our readers involved in technology transfer, legal issues, investment, strategic planning and the regulation of therapeutics.