Signs and symptoms in the diagnosis of type 1 diabetes mellitus and interventions for the management of diabetic ketoacidosis: scoping review

Concilium Pub Date : 2024-04-03 DOI:10.53660/clm-3184-24f37
Tainá de Vasconcelos Pina Pina, Natan Carlos da Cunha Costa Costa, Renata de Moraes Oliveira Avendano Avedano, B. R. L. Aguiar, Priscilla Rocha
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Abstract

Objective: To identify the most prevalent signs and symptoms in the diagnosis of Type 1 Diabetes Mellitus (DM1) in children and adolescents, as well as the signs and symptoms of Diabetic Ketoacidosis (DKA), its complications, and the nursing and medical interventions indicated for its management. Method: This is a scoping review, carried out in the LILACS, PUBMED, SCOPUS, LIVIVO, and Embase databases, with additional search in gray literature. The data were analyzed qualitatively. Results: We found 840 studies in the search, but only 10 studies met the eligibility criteria. The most frequent signs and symptoms in the diagnosis of DM1 were polydipsia (83%), polyuria (78%), and weight loss (56%). DKA symptoms were variable. The main complications of DKA were cerebral edema and death and transfer to the pediatric intensive care unit and continuous infusion of intravenous insulin were the most recommended interventions. Conclusion: Early recognition of the signs and symptoms of DM1 plays an important role in patient management, leading to rapid initiation of treatment and relevant interventions, thus preventing the occurrence of complications.
诊断 1 型糖尿病的体征和症状以及控制糖尿病酮症酸中毒的干预措施:范围界定综述
目的确定儿童和青少年 1 型糖尿病(DM1)诊断中最常见的体征和症状,以及糖尿病酮症酸中毒(DKA)的体征和症状、其并发症和治疗糖尿病酮症酸中毒的护理和医疗干预措施。方法:这是一篇范围综述,在 LILACS、PUBMED、SCOPUS、LIVIVO 和 Embase 数据库中进行了检索,并在灰色文献中进行了补充检索。对数据进行了定性分析。结果我们在搜索中发现了 840 项研究,但只有 10 项研究符合资格标准。诊断 DM1 最常见的体征和症状是多尿(83%)、多饮(78%)和体重减轻(56%)。DKA 症状不一。DKA 的主要并发症是脑水肿和死亡,转入儿科重症监护室和持续静脉注射胰岛素是最推荐的干预措施。结论早期识别DM1的症状和体征在患者管理中发挥着重要作用,可迅速启动治疗和相关干预措施,从而预防并发症的发生。
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