Nanoemulgel: An Innovative Carrier for Drug Delivery of Poorly Water-Soluble Drugs

Q3 Medicine
Prevesh Kumar, Zaira Hussain, Phool Chandra, Diksha, Varsha Raj, Navneet Verma, Alok Singh
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引用次数: 0

Abstract

Recently, the delivery of hydrophobic/ poorly water-soluble drugs has been a difficult task. Various approaches have been developed to counter the former and other main issues, such as solubility, bioavailability, etc. However, only a few formulations have successfully addressed the problems and nanoemulgels are a standout among them. The nanoemulgel drug delivery approach combines multiple benefits associated with emulsion and gel technologies to improve active moiety solubility, bioavailability, and longevity. The article discusses the present status of nanoemulgel research and development, including its preparation methods and characterization techniques. Additionally, the possible uses of nanoemulgel in targeted drug delivery and cosmetic/ personal care products are discussed. Overall, nanoemulgel technology has shown significant promise as a novel approach to augment the transport of water-insoluble moieties. With further research as well as development, it is expected to have a substantial impact on the pharmaceutical and cosmetic industries. This inclusive review highlighted the role of nanoemulgels as a promising carrier for drug delivery, with an overview of a few illustrations supporting the cause.
纳米凝胶:水溶性差药物的创新载体
近年来,疏水性/水溶性差的药物的输送一直是一项艰巨的任务。人们开发了各种方法来解决前者和其他主要问题,如溶解度、生物利用度等。然而,只有少数配方成功地解决了这些问题,纳米药物胶体就是其中的佼佼者。纳米凝胶给药方法结合了乳剂和凝胶技术的多种优点,可提高活性物质的溶解度、生物利用度和持久性。文章讨论了纳米凝胶的研究和开发现状,包括其制备方法和表征技术。此外,还讨论了纳米凝胶在靶向给药和化妆品/个人护理产品中的可能用途。总之,纳米凝胶技术作为一种增强水不溶性物质运输的新方法,已经显示出巨大的前景。随着进一步的研究和开发,预计它将对制药和化妆品行业产生重大影响。本综述强调了纳米凝胶作为一种前景广阔的药物输送载体的作用,并概述了支持这一观点的一些实例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Current Nanomedicine
Current Nanomedicine Medicine-Medicine (miscellaneous)
CiteScore
2.00
自引率
0.00%
发文量
15
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