Molecular characterization of lumpy skin disease virus in North Central Vietnam during 2021 and early 2022.

IF 0.5 4区农林科学 Q4 VETERINARY SCIENCES

Veterinaria italiana Pub Date : 2024-04-11 DOI:10.12834/VetIt.3233.22342.2

Anh Tuan Tran, H. Tran, Anh Duc Truong, Van Tai Dinh, A. Dang, N. Chu, Lanh Phan, Hoai Thi Phan, H. Nguyen, Nga Bui Thi To, H. V. Dang

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引用次数: 0

Abstract

In October 2020, the first outbreaks of lumpy skin disease (LSD) in Lang Son Province, Vietnam were reported by our laboratory. The disease had rapidly spread to the South, and it was reported in 55 of 63 provinces and cities of Vietnam by the end of 2021. The most economic loss caused by this disease occurred in the north-central region in 2021 where approximately 46,788 LSD virus (LSDV) infected cattle and buffaloes have been reported and 8,976 animals have been culled. However, the information on this pathogen circulating in this region is missing. Here, we describe the molecular characterization of LSDV circulating in north-central Vietnam in 2021 and early 2022. In total, 155 LSDV samples were collected during this period and three of these samples from each province were further characterized by Sanger sequencing analysis based on three key maker genes (GPCR, RPO30, and p32). Sequence comparison and phylogenetic analysis based on GPCR, RPO30, and p32 genes indicated that LSDV strains circulating in north-central Vietnam are closely related to previously reported strains in Vietnam regions which bordered China and all LSDV strains were 100% identical. These results show the importance of continuous monitoring and characterization of circulating LSDV strains and are important for vaccine development for the control and eradication of LSD in Vietnam.

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2021 年和 2022 年初越南中北部块皮病病毒的分子特征。

2020 年 10 月，我们的实验室报告了越南谅山省首次爆发块状皮肤病（LSD）。该病迅速向南方蔓延，到 2021 年底，越南 63 个省市中有 55 个报告了该病。2021 年，中北部地区因该病造成的经济损失最大，约有 46,788 头牛和水牛感染了 LSD 病毒（LSDV），8,976 头牛被扑杀。然而，有关这种病原体在这一地区流行的信息尚缺。在此，我们描述了 2021 年和 2022 年初在越南中北部流行的 LSDV 的分子特征。在此期间，我们共采集了 155 份 LSDV 样本，并通过桑格测序分析（Sanger sequencing analysis）对每个省的其中三份样本的三个关键制造基因（GPCR、RPO30 和 p32）进行了进一步鉴定。基于 GPCR、RPO30 和 p32 基因的序列比较和系统进化分析表明，在越南中北部流行的 LSDV 株系与之前报道的与中国接壤的越南地区的株系关系密切，所有 LSDV 株系均 100%相同。这些结果表明了对流行的 LSDV 株系进行持续监测和特征描述的重要性，并对越南控制和根除 LSD 的疫苗开发具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinaria italiana VETERINARY SCIENCES-

CiteScore

1.50

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The journal was created as the Croce Azzurra in 1950. A quarterly peer-reviewed journal devoted to veterinary public health and other aspects of veterinary science and medicine, Veterinaria Italiana is published by the Istituto Zooprofilattico Sperimentale dell’Abruzzo e del Molise ‘G. Caporale’ (Istituto Zooprofilattico Sperimentale dell''Abruzzo e del Molise) in Teramo, Italy. The goal of the journal is to provide an international platform for veterinary public health information from Italy and other countries, particularly those in Eastern Europe and Africa, Asia and South America. Veterinarians and veterinary public health specialists are encouraged to share their knowledge and experience on this platform.