Antimicrobial susceptibility patterns of aerobic bacteria isolated from canine urinary samples in South East Queensland, 2013 to 2018

IF 1.3 4区 农林科学 Q2 VETERINARY SCIENCES
C Mack, JS Gibson, E Meler, S Woldeyohannes, N Yuen, A Herndon
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Abstract

Urinary tract infections are a common diagnosis in dogs presenting to veterinary practice. Veterinarians often treat suspected infections empirically, either in the absence of culture and susceptibility testing results or whilst waiting for them. This study aimed to identify the bacteria most frequently isolated from canine urinary samples and their antimicrobial susceptibility patterns in South East Queensland (SEQ) to help guide responsible empirical antimicrobial prescription by the veterinary community in this geographical location. Cumulative antibiograms were generated from the results of 1284 culture-positive urinary samples in SEQ, obtained from a commercial veterinary laboratory over a 5-year period. Escherichia coli was the most commonly isolated bacterial species (43%), followed by Staphylococcus spp. (23%), Proteus spp. (21%) and Enterococcus spp. (10%). Of the six most common isolates, 97% had susceptibility to at least one low-importance antimicrobial. Susceptibility to the low-importance and first-line antimicrobial recommendation, amoxicillin, was 81% for E. coli and 24% for Staphylococcus spp. Susceptibility of both E. coli and Staphylococcus spp. to medium-importance and commonly recommended empirical antimicrobials, trimethoprim sulphonamides and amoxicillin–clavulanic acid was ≥85% and >92% for high-importance antimicrobials enrofloxacin and ceftiofur. Of the E. coli and Staphylococcus spp. isolates, 8.8% and 4%, respectively, were considered multidrug resistant. There was no increase in resistance to antimicrobials detected over the study period. Susceptibilities suggest low- and medium-importance antimicrobials remain acceptable first-line empirical treatments. However, this should be continually assessed and updated using local surveillance data.

2013 年至 2018 年昆士兰东南部犬尿液样本中分离出的需氧菌的抗菌药敏感性模式。
在兽医诊所就诊的狗中,尿路感染是一种常见的诊断方法。兽医通常会在没有培养和药敏试验结果的情况下或在等待结果期间对疑似感染进行经验性治疗。本研究旨在确定昆士兰州东南部(SEQ)最常从犬尿液样本中分离出的细菌及其抗菌药敏感性模式,以帮助指导该地区兽医界负责任地开具经验性抗菌药处方。根据 5 年间从一家商业兽医实验室获得的 1284 份昆士兰东南部地区培养阳性尿液样本的结果,绘制了累积抗生素图谱。大肠杆菌是最常见的分离细菌(43%),其次是葡萄球菌属(23%)、变形杆菌属(21%)和肠球菌属(10%)。在六种最常见的分离菌株中,97%对至少一种低重要性抗菌药具有敏感性。大肠杆菌和葡萄球菌对中等重要和常用抗菌药阿莫西林的敏感性分别为 81%和 24%。大肠杆菌和葡萄球菌对中等重要的常用经验性抗菌药三甲氧苄啶、磺胺类药物和阿莫西林-克拉维酸的敏感性≥85%,对重要抗菌药恩诺沙星和头孢噻呋的敏感性>92%。在大肠杆菌和葡萄球菌属分离物中,分别有 8.8% 和 4% 被认为具有多重耐药性。在研究期间检测到的抗菌药耐药性没有增加。敏感性表明,中低重要性抗菌药物仍是可接受的一线经验性治疗药物。不过,应利用当地的监测数据不断对其进行评估和更新。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Australian Veterinary Journal
Australian Veterinary Journal 农林科学-兽医学
CiteScore
2.40
自引率
0.00%
发文量
85
审稿时长
18-36 weeks
期刊介绍: Over the past 80 years, the Australian Veterinary Journal (AVJ) has been providing the veterinary profession with leading edge clinical and scientific research, case reports, reviews. news and timely coverage of industry issues. AJV is Australia''s premier veterinary science text and is distributed monthly to over 5,500 Australian Veterinary Association members and subscribers.
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