Prevalence of SARS-CoV-2 in newborns born to SARS-CoV-2-positive mothers at 2 weeks of life

Frontiers in Pediatrics Pub Date : 2024-04-25 DOI:10.3389/fped.2024.1381104

Sophia Jan, Robert Katz, David Fagan, Telmo Santos, Joanna C. Beachy, C. Steinway, Jack Chen, Alina Tsouristakis, Briana Mancenido, Christy Leung, Emily Moore, Estelle Wilson, Lorna Lin, Michael Harte, M. Katzow, Lorry G. Rubin

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Abstract

Limited evidence exists on management recommendations for neonates born to SARS-CoV-2-positive mothers. This study looked at transmission risk of neonates presenting for primary care in a large regional health system within New York during the early months of the COVID-19 pandemic.This was a prospective, observational study of newborns born to SARS-CoV-2-positive mothers presenting at any of the 19 Northwell Health-Cohen Children's Medical Center primary care practices who underwent another oropharyngeal/nasopharyngeal swab for detection of SARS-CoV-2 by day of life (DOL) 14.Among 293 newborns born to SARS-CoV-2-positive mothers who were negative at birth, 222 were retested at DOL 14, corresponding to times with different predominant strains. Of these, seven tested positive but had no symptoms.The overall low transmission rates and absence of symptomatic infection support the safety of direct breastfeeding after hospital discharge with appropriate hand and breast hygiene.

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SARS-CoV-2 阳性母亲所生新生儿出生两周时的 SARS-CoV-2 感染率

对于 SARS-CoV-2 阳性母亲所生新生儿的管理建议，目前证据有限。本研究调查了在 COVID-19 大流行的最初几个月中，在纽约一个大型地区医疗系统接受初级护理的新生儿的传播风险。这是一项前瞻性观察研究，研究对象是 SARS-CoV-2 阳性母亲所生的新生儿，这些新生儿在诺斯韦尔健康-科恩儿童医学中心的 19 家初级保健诊所中的任何一家就诊，并在出生后第 14 天（DOL）再次接受口咽/鼻咽拭子检测 SARS-CoV-2。在 SARS-CoV-2 阳性母亲所生的 293 名出生时检测结果为阴性的新生儿中，有 222 名在出生后第 14 天（DOL）接受了复检，这与主要菌株不同的时间相对应。总体传播率较低且无症状感染，这支持了出院后通过适当的手部和乳房卫生直接进行母乳喂养的安全性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Frontiers in Pediatrics

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