Charlene N. Agnew, William E. Sullivan, Kate E. Derrenbacker, Henry S. Roane, Andrew R. Craig
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引用次数: 0
Abstract
This pilot study aimed to examine voluntary abstinence from, and relapse of, ethanol seeking following removal of alternative nondrug reinforcement using a concurrent-chains arrangement. Rats first were trained to self-administer ethanol during a baseline condition. Next, they were presented with choices between responding for ethanol and sucrose during the initial link of a concurrent-chains schedule. Following their initial-link choice, they entered a terminal link in which they could respond exclusively for the reinforcer associated with their initial-link choice. To test for relapse, the same concurrent-chains procedure was arranged except that sucrose reinforcement was suspended from the sucrose-correlated terminal link. Overall, four out of the five rats showed a consistent preference for sucrose over ethanol during the voluntary-abstinence phase. When sucrose reinforcement was suspended during the relapse test, ethanol seeking increased for all rats.
期刊介绍：
Learning and Motivation features original experimental research devoted to the analysis of basic phenomena and mechanisms of learning, memory, and motivation. These studies, involving either animal or human subjects, examine behavioral, biological, and evolutionary influences on the learning and motivation processes, and often report on an integrated series of experiments that advance knowledge in this field. Theoretical papers and shorter reports are also considered.
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