H4K20me3, H3K4me2 and H3K9me2 mediate the effect of ER on prognosis in breast cancer

IF 2.9 3区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY
Cheng-Kun Xiao, Yuexiang Ren, Qianxin Chen, Yuanzhong Yang, Luying Tang, Lin Xu, Zefang Ren
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引用次数: 0

Abstract

Previous studies have indicated that histone methylations act as mediators in the relationship between oestrogen receptor (ER) and breast cancer prognosis, yet the mediating role has never been ass...
H4K20me3、H3K4me2 和 H3K9me2 介导 ER 对乳腺癌预后的影响
以往的研究表明,组蛋白甲基化在雌激素受体(ER)与乳腺癌预后之间的关系中起着介导作用,但这种介导作用从未被证实。
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来源期刊
Epigenetics
Epigenetics 生物-生化与分子生物学
CiteScore
6.80
自引率
2.70%
发文量
82
审稿时长
3-8 weeks
期刊介绍: Epigenetics publishes peer-reviewed original research and review articles that provide an unprecedented forum where epigenetic mechanisms and their role in diverse biological processes can be revealed, shared, and discussed. Epigenetics research studies heritable changes in gene expression caused by mechanisms others than the modification of the DNA sequence. Epigenetics therefore plays critical roles in a variety of biological systems, diseases, and disciplines. Topics of interest include (but are not limited to): DNA methylation Nucleosome positioning and modification Gene silencing Imprinting Nuclear reprogramming Chromatin remodeling Non-coding RNA Non-histone chromosomal elements Dosage compensation Nuclear organization Epigenetic therapy and diagnostics Nutrition and environmental epigenetics Cancer epigenetics Neuroepigenetics
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