Untimely surgery for stent-fracture-related death after transjugular intrahepatic portosystemic shunt: a case report

IF 3.3 3区 医学 Q2 PHARMACOLOGY & PHARMACY
Yunjiang Li, Junhui Sun, Tanyang Zhou, Weiwei Wang, Guowei Wang, Qingming Hou, Zuhua Chen, Qiang Wang, Keyang Xu, Yunfeng Ye, Jianfeng Bao
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Abstract

Transjugular intrahepatic portosystemic shunt (TIPS) is a life-saving procedure for patients with severe portal hypertension and persistent variceal bleeding. Stent fracture is a rare and severe complication; however, its cause and mechanisms remain poorly defined. This case helps understand the factors contributing to its occurrence, complications, and subsequent poor outcomes. A 63-year-old male was presented with ruptured bare stent after a TIPS procedure. The upper edge of the bare stent was ruptured, and its fraction subsequently migrated to the entrance of the right atrium. Meanwhile, a mural thrombus was formed in the inferior vena cava. A surgery for the removal of free fracture was planned for preventing the form of pulmonary embolism. Before the surgery, the fracture was shifted to the right inferior pulmonary artery. Therefore, the surgery was canceled for further evaluation. Then, hematemesis suddenly occurred with a high possibility of variceal bleeding and/or gastric ulcer bleeding. Despite comprehensive treatments, the patient symptoms were still worsened with the development of chest tightness, shortness of breath, severe hypoxia, and heart failure. Finally, the patient succumbed to systemic multiorgan failure and death. Taken together, a ruptured unstable stent should be removed as early as the patient is hemodynamically stable, as it is difficult to balance between hemostasis therapy and anticoagulation treatment in patients with liver-cirrhosis-related severe portal hypertension. Physicians should be on high alert of the potential complications of bare stent rapture after TIPS.
经颈静脉肝内门体分流术后支架断裂导致死亡,手术不及时:病例报告
经颈静脉肝内门体分流术(TIPS)是一种挽救严重门静脉高压和持续静脉曲张出血患者生命的手术。支架断裂是一种罕见的严重并发症,但其原因和机制仍未明确。本病例有助于了解导致支架断裂、并发症和不良预后的因素。一名 63 岁的男性在接受 TIPS 手术后出现裸支架断裂。裸支架上缘破裂,其部分随后移至右心房入口处。同时,下腔静脉内形成了壁血栓。为防止出现肺栓塞,计划进行手术切除游离骨折。手术前,骨折已移至右下肺动脉。因此,手术被取消,以做进一步评估。随后,患者突然出现吐血,极有可能是静脉曲张出血和/或胃溃疡出血。尽管进行了综合治疗,但患者症状仍然恶化,出现胸闷、气短、严重缺氧和心力衰竭。最后,患者因全身多器官功能衰竭而死亡。综上所述,由于肝硬化相关重度门静脉高压症患者很难在止血治疗和抗凝治疗之间取得平衡,因此应在患者血流动力学稳定后尽早取出破裂的不稳定支架。医生应高度警惕 TIPS 术后裸支架脱落的潜在并发症。
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来源期刊
Therapeutic Advances in Chronic Disease
Therapeutic Advances in Chronic Disease Medicine-Medicine (miscellaneous)
CiteScore
6.20
自引率
0.00%
发文量
108
审稿时长
12 weeks
期刊介绍: Therapeutic Advances in Chronic Disease publishes the highest quality peer-reviewed research, reviews and scholarly comment in the drug treatment of all chronic diseases. The journal has a strong clinical and pharmacological focus and is aimed at clinicians and researchers involved in the medical treatment of chronic disease, providing a forum in print and online for publishing the highest quality articles in this area.
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