Establishing national reference materials for genetic testing of cytochrome P450.

IF 1.7 3区医学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Pharmacogenetics and genomics Pub Date : 2024-04-15 DOI:10.1097/fpc.0000000000000532

Zheng Jia, Junju Huang, Ying Yang, Yong Yang, Wei Lin, Shoufang Qu, Nan Sun, Wenxin Zhang, Lulu Han, Jie Huang

引用次数: 0

Abstract

Reference materials for in-vitro diagnostic reagents play a critical role in determining the quality of reagents and ensuring the accuracy of clinical test results. This study aimed to establish a national reference material (NRM) for detecting cytochrome P450 (CYP) genes related to drug metabolism by screening databases on the Chinese population to identify CYP gene polymorphism characteristics.

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建立细胞色素 P450 基因检测国家参考资料。

体外诊断试剂的标准物质在确定试剂质量和确保临床检验结果的准确性方面起着至关重要的作用。本研究旨在通过筛选中国人群数据库，确定CYP基因多态性特征，从而建立检测与药物代谢相关的细胞色素P450（CYP）基因的国家参考物质（NRM）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pharmacogenetics and genomics 医学-生物工程与应用微生物

CiteScore

3.20

自引率

3.80%

发文量

审稿时长

3 months

期刊介绍： Pharmacogenetics and Genomics is devoted to the rapid publication of research papers, brief review articles and short communications on genetic determinants in response to drugs and other chemicals in humans and animals. The Journal brings together papers from the entire spectrum of biomedical research and science, including biochemistry, bioinformatics, clinical pharmacology, clinical pharmacy, epidemiology, genetics, genomics, molecular biology, pharmacology, pharmaceutical sciences, and toxicology. Under a single cover, the Journal provides a forum for all aspects of the genetics and genomics of host response to exogenous chemicals: from the gene to the clinic.