Investigation of the morphometric characteristics of internal carotid artery between sexes and in patients with intracranial aneurysms

IF 1.2 4区医学 Q3 ANATOMY & MORPHOLOGY

Surgical and Radiologic Anatomy Pub Date : 2024-04-17 DOI:10.1007/s00276-024-03351-8

Yigit Cevik, Hasan Bilen Onan, Huseyin Erdem, Emine Dondu Kizilkanat, Sevinc Puren Yucel, Ozkan Oguz

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Abstract

Purpose

The purpose of this study is to investigate the morphometric properties of the internal carotid artery (ICA) by measuring the diameters and angles of its segments and exploring variations related to sex and the presence of aneurysms.

Methods

Digital subtraction angiography (DSA) images were utilized from 130 aneurysm patients and 75 non-aneurysm individuals to create 3D ICA models using 3D Slicer software. Segment diameters were measured via Autodesk Meshmixer 3.5.474 and angles were evaluated using ImageJ software.

Results

In total, DSA images of 130 aneurysm patients and 75 individuals with normally reported carotid systems were evaluated. It was found that the intracranial aneurysms (IAs) were predominantly formed on the anterior cerebral artery (ACA) in males (%43), whereas in females IAs were frequently localized in the C6 segment (31.7%) and middle cerebral artery (MCA) (30.2%). In the control group, the evaluation of gender differences in segment diameters and angles revealed that males had significantly larger C4 and C5 segment diameters (4.62 vs. 4.32 mm and 4.41 vs. 4.09 mm, respectively) and a greater C6 angle (146.9° vs. 139.7°) compared to females. Comparisons between patients with an aneurysm at the anterior cerebral artery (ACA) and the control group revealed that the ACA group had wider diameters in the C1 (4.88 vs. 4.53 mm), C3 (4.65 vs. 4.4 mm), C5 (4.51 vs. 4.25 mm), and ACA (2.36 vs. 2.06 mm) segments. Additionally, the ACA group had wider angles in the ACA (104.1° vs. 94.1°) and C6 segments (147.7° vs. 143.3°), whereas the control group exhibited wider angles in the middle cerebral artery (MCA) segment (141.5° vs. 135.5°) compared to the ACA aneurysm group. Patients with anterior cerebral artery (ACA) aneurysms exhibited larger diameters in C1, C3, C5, C6, and ACA segments compared to the control group. Additionally, while the control group had larger MCA angle, patients with ACA aneurysms had larger angles in C6 segment and ACA.

Conclusion

Our results demonstrated that formation of aneurysms is affected by anatomical configuration of the ICA as well as sex characteristics, particularly regarding the ACA and MCA bifurcation angles, which showed associations with aneurysms in the respective branches.

Abstract Image

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不同性别和颅内动脉瘤患者颈内动脉形态特征的研究

目的本研究旨在通过测量颈内动脉（ICA）节段的直径和角度来研究其形态特性，并探讨与性别和动脉瘤存在相关的变化。方法利用 130 名动脉瘤患者和 75 名非动脉瘤患者的数字减影血管造影（DSA）图像，使用 3D Slicer 软件创建三维 ICA 模型。结果共评估了 130 名动脉瘤患者和 75 名颈动脉系统正常者的 DSA 图像。结果发现，男性的颅内动脉瘤（IAs）主要形成于大脑前动脉（ACA）（%43），而女性的颅内动脉瘤（IAs）则经常位于 C6 段（31.7%）和大脑中动脉（MCA）（30.2%）。在对照组中，通过评估节段直径和角度的性别差异发现，与女性相比，男性的 C4 和 C5 节段直径明显更大（分别为 4.62 mm 对 4.32 mm 和 4.41 mm 对 4.09 mm），C6 角度更大（146.9° 对 139.7°）。大脑前动脉（ACA）动脉瘤患者与对照组的比较显示，ACA 组患者的 C1（4.88 对 4.53 毫米）、C3（4.65 对 4.4 毫米）、C5（4.51 对 4.25 毫米）和 ACA（2.36 对 2.06 毫米）节段的直径更宽。此外，与 ACA 动脉瘤组相比，ACA 组在 ACA 节段（104.1° 对 94.1°）和 C6 节段（147.7° 对 143.3°）的角度更宽，而对照组在大脑中动脉（MCA）节段（141.5° 对 135.5°）的角度更宽。与对照组相比，大脑前动脉（ACA）动脉瘤患者的 C1、C3、C5、C6 和 ACA 段直径更大。结论我们的研究结果表明，动脉瘤的形成受 ICA 解剖结构和性别特征的影响，尤其是 ACA 和 MCA 分叉角，这两个角度与相应分支的动脉瘤有关联。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Surgical and Radiologic Anatomy ANATOMY & MORPHOLOGY-RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

CiteScore

2.70

自引率

14.30%

发文量

183

审稿时长

4-8 weeks

期刊介绍： Anatomy is a morphological science which cannot fail to interest the clinician. The practical application of anatomical research to clinical problems necessitates special adaptation and selectivity in choosing from numerous international works. Although there is a tendency to believe that meaningful advances in anatomy are unlikely, constant revision is necessary. Surgical and Radiologic Anatomy, the first international journal of Clinical anatomy has been created in this spirit. Its goal is to serve clinicians, regardless of speciality-physicians, surgeons, radiologists or other specialists-as an indispensable aid with which they can improve their knowledge of anatomy. Each issue includes: Original papers, review articles, articles on the anatomical bases of medical, surgical and radiological techniques, articles of normal radiologic anatomy, brief reviews of anatomical publications of clinical interest. Particular attention is given to high quality illustrations, which are indispensable for a better understanding of anatomical problems. Surgical and Radiologic Anatomy is a journal written by anatomists for clinicians with a special interest in anatomy.