Effects of nucleoside analogues, lipophilic prodrugs and elaidic acids on core signaling pathways in cancer cells

IF 1.1 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Marika A. Frańczak, Claudine van der Sande, Elisa Giovannetti, Godefridus J. Peters
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引用次数: 0

Abstract

Nucleoside analogs such as gemcitabine (GEM; dFdC) and cytarabine (Ara-C) require nucleoside transporters to enter cells, and deficiency in equilibrative nucleoside transporter 1 (ENT1) can lead to...
核苷类似物、亲脂原药和鞣酸对癌细胞核心信号通路的影响
核苷类似物(如吉西他滨(GEM;dFdC)和阿糖胞苷(Ara-C))需要核苷转运体才能进入细胞,而平衡核苷转运体1(ENT1)的缺乏可导致核苷代谢紊乱。
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来源期刊
Nucleosides, Nucleotides & Nucleic Acids
Nucleosides, Nucleotides & Nucleic Acids 生物-生化与分子生物学
CiteScore
2.60
自引率
7.70%
发文量
91
审稿时长
6 months
期刊介绍: Nucleosides, Nucleotides & Nucleic Acids publishes research articles, short notices, and concise, critical reviews of related topics that focus on the chemistry and biology of nucleosides, nucleotides, and nucleic acids. Complete with experimental details, this all-inclusive journal emphasizes the synthesis, biological activities, new and improved synthetic methods, and significant observations related to new compounds.
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