Photodynamic application in diagnostic procedures and treatment of non-melanoma skin cancers

IF 3.8 2区 医学 Q2 ONCOLOGY
Zhiya Yang, Dongmei Li, Dongmei Shi
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引用次数: 0

Abstract

Skin tumors commonly seen in dermatology are involved in all layers of the skin and appendages. While biopsy of affected skin remains an essential method to confirm diagnosis and to predicate tumor prognosis, it has its limitations. Recently, photodynamic diagnosis (PDD) has demonstrated high sensitivity in detecting affected skin and mucosal tissues, providing valuable guidance for precision surgery to resect skin and mucosal tumors. In this review, we summarized the literatures concerning the applications of PDD in diagnostic process and treatment of skin and mucosal conditions such as actinic keratoses (AK), basal cell carcinoma (BCC), squamous cell carcinoma (SCC), Bowen’s disease (BD) and extramammary Paget’s disease (EMPD). The findings suggest that PDD holds substantial promise for expanding clinical applications and deserves further research exploration.

光动力在非黑素瘤皮肤癌诊断和治疗中的应用
皮肤科常见的皮肤肿瘤累及各层皮肤和附属器官。虽然对受影响皮肤进行活检仍是确诊和预测肿瘤预后的重要方法,但它也有其局限性。最近,光动力诊断(PDD)在检测受累皮肤和粘膜组织方面表现出极高的灵敏度,为切除皮肤和粘膜肿瘤的精准手术提供了宝贵的指导。在这篇综述中,我们总结了光动力诊断在皮肤和粘膜疾病诊断和治疗过程中的应用,如光化性角化病(AK)、基底细胞癌(BCC)、鳞状细胞癌(SCC)、鲍温氏病(BD)和乳腺外帕吉特氏病(EMPD)。 研究结果表明,光动力诊断在扩大临床应用方面前景广阔,值得进一步研究探索。
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来源期刊
CiteScore
7.10
自引率
0.00%
发文量
113
审稿时长
>12 weeks
期刊介绍: This journal aims to review the most important, recently published treatment option advances in the field of oncology. By providing clear, insightful, balanced contributions by international experts, the journal intends to facilitate worldwide approaches to cancer treatment. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as endocrine tumors, lymphomas, neuro-oncology, and cancers of the breast, head and neck, lung, skin, gastrointestinal tract, and genitourinary region. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known oncologists, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.
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