Stimuli-responsive Graphene-Polysaccharide Nanocomposites for Drug Delivery and Tissue Engineering

IF 1.7 4区化学 Q3 CHEMISTRY, ORGANIC

Current organic synthesis Pub Date : 2024-04-16 DOI:10.2174/0115701794298435240324175513

Arman Seifallahi Teymourlouei, Seyed Morteza Naghib, M. R. Mozafari

引用次数: 0

Abstract

:: Natural polysaccharide-based nanoparticles are known for their non-toxic nature and diverse medical applications. Graphene oxide (GO) nanoparticles show potential in cancer treat-ment due to their ability to target medication delivery and influence ROS generation. These nanocomposites are versatile in gene transport, therapy, and photodynamic therapy, especially when surface-modified. Proper dispersion and functionalization of GO in polymer matrices are crucial, with examples like hyaluronic acid-functionalized GO offering versatile platforms for cancer drug administration. The potential of graphene oxide extends to cancer phototherapy, electronic nanowires, hydrogels, antibacterial nanocomposites, and environmental applications. When activated by polysaccharides, graphene-based nanocomposites exhibit anti-inflammatory and anticancer properties, making them valuable across various industries, including water treat-ment.

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用于药物输送和组织工程的刺激响应型石墨烯-多糖纳米复合材料

::以天然多糖为基础的纳米粒子以其无毒性和多样化的医疗应用而闻名。氧化石墨烯（GO）纳米粒子具有靶向给药和影响 ROS 生成的能力，因此在癌症治疗方面具有潜力。这些纳米复合材料在基因传输、治疗和光动力疗法方面用途广泛，尤其是在表面修饰后。氧化石墨烯在聚合物基质中的适当分散和功能化至关重要，透明质酸功能化氧化石墨烯等实例为癌症给药提供了多功能平台。氧化石墨烯的潜力还包括癌症光疗、电子纳米线、水凝胶、抗菌纳米复合材料和环境应用。经多糖激活后，石墨烯基纳米复合材料具有消炎和抗癌特性，因此在包括水处理在内的各行各业都很有价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current organic synthesis 化学-有机化学

CiteScore

3.40

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Current Organic Synthesis publishes in-depth reviews, original research articles and letter/short communications on all areas of synthetic organic chemistry i.e. asymmetric synthesis, organometallic chemistry, novel synthetic approaches to complex organic molecules, carbohydrates, polymers, protein chemistry, DNA chemistry, supramolecular chemistry, molecular recognition and new synthetic methods in organic chemistry. The frontier reviews provide the current state of knowledge in these fields and are written by experts who are internationally known for their eminent research contributions. The journal is essential reading to all synthetic organic chemists. Current Organic Synthesis should prove to be of great interest to synthetic chemists in academia and industry who wish to keep abreast with recent developments in key fields of organic synthesis.

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