Physicochemical Perspective of Biological Heterogeneity

IF 3.7 Q2 CHEMISTRY, PHYSICAL
Karina Kwapiszewska
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引用次数: 0

Abstract

The vast majority of chemical processes that govern our lives occur within living cells. At the core of every life process, such as gene expression or metabolism, are chemical reactions that follow the fundamental laws of chemical kinetics and thermodynamics. Understanding these reactions and the factors that govern them is particularly important for the life sciences. The physicochemical environment inside cells, which can vary between cells and organisms, significantly impacts various biochemical reactions and increases the extent of population heterogeneity. This paper discusses using physical chemistry approaches for biological studies, including methods for studying reactions inside cells and monitoring their conditions. The potential for development in this field and possible new research areas are highlighted. By applying physical chemistry methodology to biochemistry in vivo, we may gain new insights into biology, potentially leading to new ways of controlling biochemical reactions.

Abstract Image

从物理化学角度看生物异质性
支配我们生命的绝大多数化学过程都发生在活细胞内。基因表达或新陈代谢等每个生命过程的核心都是遵循化学动力学和热力学基本定律的化学反应。了解这些反应及其影响因素对生命科学尤为重要。细胞内的物理化学环境因细胞和生物体而异,对各种生化反应产生重大影响,并增加了群体异质性的程度。本文将讨论利用物理化学方法进行生物研究,包括研究细胞内反应和监测其状况的方法。本文强调了这一领域的发展潜力和可能的新研究领域。通过将物理化学方法应用于体内生物化学,我们可能会对生物学有新的认识,并有可能开发出控制生物化学反应的新方法。
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来源期刊
CiteScore
3.70
自引率
0.00%
发文量
0
期刊介绍: ACS Physical Chemistry Au is an open access journal which publishes original fundamental and applied research on all aspects of physical chemistry. The journal publishes new and original experimental computational and theoretical research of interest to physical chemists biophysical chemists chemical physicists physicists material scientists and engineers. An essential criterion for acceptance is that the manuscript provides new physical insight or develops new tools and methods of general interest. Some major topical areas include:Molecules Clusters and Aerosols; Biophysics Biomaterials Liquids and Soft Matter; Energy Materials and Catalysis
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