Outcome associated with use of winged expandable titanium cage following cervical corpectomy: an institutional experience

IF 0.7 Q4 CLINICAL NEUROLOGY
Anand Prakash, Rohit Bharti, Ganesh Chauhan, Gautam Dutta, Chandra Bhushan Sahay
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Abstract

In patients with spinal cord compression behind the cervical vertebra who presented with myelopathy, one of the treatment modalities is anterior cervical corpectomy followed by insertion of graft or implant. Autogenous bone graft has been the choice of implant for corpectomy in the past, but due to donor site complications, it has been majorly replaced with other implants like titanium made expandable and non-expandable cages. Studies on titanium made implants for cervical compressive myelopathy have mostly focused on expandable cages with separate plates. Studies on hybrid cages and winged expandable titanium cages with (WETC) are lacking, especially in patients with poor Nurick grade. Here, we present clinical outcomes and side effects of WETC use following cervical corpectomy in 81 participants from a tertiary care center from Eastern India with 6 months of follow-up. We observed a considerable improvement in clinical outcomes which was measured using Nurick grade as mean scores changed from 4.06 ± 0.85 during the pre-operative stage to 2.85 ± 1.16 post-operation (P < 0.05). There was also a considerable improvement in the pain status as in the pre-operative stage there were three patients with mild pain, 53 with moderate and 25 with severe pain, but post-operation there were 53 patients with mild pain, only two with moderate pain and none with severe pain (P < 0.00001). In these participants, we observed that post-surgical Nurick grade was not associated with age, gender or time since first symptoms but was strongly associated with pre-surgical Nurick grade at P < 0.05. With WETC (in situ plate), we were able to obtain good outcomes with less serious complication in patients with poor Nurick grade. As size of implant is prefixed and can be expanded in WETC, it takes relatively less time to insert, thus leading to shorter operative time. With good endplate preparation and avoiding over expansion of cage, WETC avoids complications.
颈椎后路切除术后使用带翼可扩张钛笼的相关结果:机构经验
对于颈椎后方脊髓受压并伴有脊髓病的患者,治疗方法之一是进行颈椎前路椎体切除术,然后植入移植骨或植入物。过去,自体骨移植一直是颈椎椎弓根切除术的首选植入物,但由于供体部位的并发症,自体骨移植已被其他植入物(如钛制可扩张和不可扩张骨笼)所取代。有关钛制植入物治疗颈椎压迫性脊髓病的研究主要集中在带有独立钢板的可扩张脊髓笼上。关于混合型钛笼和带翼可扩张钛笼(WETC)的研究还很缺乏,尤其是针对Nurick分级较低的患者。在此,我们对来自印度东部一家三级医疗中心的 81 名患者进行了为期 6 个月的随访,介绍了颈椎椎体切除术后使用 WETC 的临床效果和副作用。我们观察到,使用 Nurick 分级衡量的临床结果有了显著改善,平均得分从术前的 4.06 ± 0.85 降至术后的 2.85 ± 1.16(P < 0.05)。疼痛状况也有显著改善,术前有 3 名患者轻度疼痛,53 名患者中度疼痛,25 名患者重度疼痛,但术后有 53 名患者轻度疼痛,仅有 2 名患者中度疼痛,无重度疼痛患者(P < 0.00001)。在这些参与者中,我们观察到手术后的 Nurick 分级与年龄、性别或首次出现症状的时间无关,但与手术前的 Nurick 分级密切相关,P < 0.05。通过使用 WETC(原位钢板),我们能够在 Nurick 分级较低的患者中取得较好的疗效和较少的严重并发症。由于 WETC 中植入物的尺寸是预先确定的,并且可以扩大,因此植入时间相对较短,从而缩短了手术时间。WETC 具有良好的终板准备,可避免骨笼过度扩张,从而避免并发症的发生。
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