Exploiting gut microbial traits and trade-offs in microbiome-based therapeutics

Bin Liu, Daniel Rios Garza, Pallabita Saha, Xingjian Zhou, Karoline Faust
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Abstract

The clinical translation of therapeutics on the basis of human gut microorganisms is hampered by our limited knowledge of how microbes survive and adapt to fluctuating conditions in the gut. The systematic exploration of gut microbiome survival strategies and trade-offs will thus enable the design of more efficient microbiome-based interventions.

Abstract Image

利用肠道微生物特性和权衡基于微生物组的疗法
由于我们对微生物如何在肠道中生存和适应波动条件的了解有限,以人类肠道微生物为基础的疗法的临床转化受到了阻碍。因此,系统地探索肠道微生物群的生存策略和权衡,将有助于设计出更有效的基于微生物群的干预措施。
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