New tools to study renal fibrogenesis.

IF 2.2 3区医学 Q3 PERIPHERAL VASCULAR DISEASE

Current Opinion in Nephrology and Hypertension Pub Date : 2024-04-08 DOI:10.1097/mnh.0000000000000988

Xian Liao, Emilia Scheidereit, Christoph Kuppe

引用次数: 0

Abstract

Kidney fibrosis is a key pathological aspect and outcome of chronic kidney disease (CKD). The advent of multiomic analyses using human kidney tissue, enabled by technological advances, marks a new chapter of discovery in fibrosis research of the kidney. This review highlights the rapid advancements of single-cell and spatial multiomic techniques that offer new avenues for exploring research questions related to human kidney fibrosis development.

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研究肾脏纤维形成的新工具。

肾脏纤维化是慢性肾脏病（CKD）的一个重要病理方面和结果。在技术进步的推动下，利用人体肾脏组织进行多组学分析的出现，标志着肾脏纤维化研究的发现翻开了新的篇章。本综述重点介绍了单细胞和空间多组学技术的快速发展，这些技术为探索与人类肾脏纤维化发展相关的研究问题提供了新的途径。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Opinion in Nephrology and Hypertension 医学-泌尿学与肾脏学

CiteScore

5.70

自引率

6.20%

发文量

132

审稿时长

6-12 weeks

期刊介绍： A reader-friendly resource, Current Opinion in Nephrology and Hypertension provides an up-to-date account of the most important advances in the field of nephrology and hypertension. Each issue contains either two or three sections delivering a diverse and comprehensive coverage of all the key issues, including pathophysiology of hypertension, circulation and hemodynamics, and clinical nephrology. Current Opinion in Nephrology and Hypertension is an indispensable journal for the busy clinician, researcher or student.