Inside Front Cover: Cerebrospinal fluid efflux through dynamic paracellular pores on venules as a missing piece of the brain drainage system (EXP2 2/2024)

Yaqiong Dong, Ting Xu, Lan Yuan, Yahan Wang, Siwang Yu, Zhi Wang, Shizhu Chen, Chunhua Chen, Weijiang He, Tessandra Stewart, Weiguang Zhang, Xiaoda Yang
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引用次数: 0

Abstract

While asleep, the cerebrospinal fluid (CSF) flush over the brain parenchyma via pathways generated by neuroglia cells. The interstitial fluid (ISF) solutes containing metabolic wastes/toxins such as Aβ are collected in the paravenous space, where the CSF-ISF fluid eventually exit into blood through dynamically assembled, trumpet-shaped pores formed by vascular endothelial cells.

Abstract Image

封面内页:脑脊液通过静脉上的动态旁孔流出是大脑排水系统缺失的一环(EXP2 2/2024)
睡眠时,脑脊液(CSF)通过神经胶质细胞产生的路径冲刷脑实质。间质液(ISF)中含有代谢废物/毒素(如 Aβ)的溶质聚集在蛛网膜旁间隙,CSF-ISF 液体最终通过由血管内皮细胞动态组装形成的喇叭形孔隙排入血液。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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CiteScore
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