Perspective: The complex relationship between charge, mobility, and gas-phase protein structure

IF 1.9 3区化学 Q3 BIOCHEMICAL RESEARCH METHODS

Journal of Mass Spectrometry Pub Date : 2024-04-11 DOI:10.1002/jms.5013

Ian K. Webb

引用次数: 0

Abstract

Ion mobility spectrometry coupled to mass spectrometry (IMS/MS) is a widely used tool for biomolecular separations and structural elucidation. The application of IMS/MS has resulted in exciting developments in structural proteomics and genomics. This perspective gives a brief background of the field, addresses some of the important issues in making structural measurements, and introduces complementary techniques.

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透视：电荷、迁移率和气相蛋白质结构之间的复杂关系

离子迁移谱质谱联用仪（IMS/MS）是一种广泛用于生物分子分离和结构阐释的工具。IMS/MS 的应用为结构蛋白质组学和基因组学带来了令人振奋的发展。本视角简要介绍了这一领域的背景，阐述了结构测量中的一些重要问题，并介绍了补充技术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Mass Spectrometry 化学-光谱学

CiteScore

5.10

自引率

0.00%

发文量

审稿时长

1.5 months

期刊介绍： The Journal of Mass Spectrometry publishes papers on a broad range of topics of interest to scientists working in both fundamental and applied areas involving the study of gaseous ions. The aim of JMS is to serve the scientific community with information provided and arranged to help senior investigators to better stay abreast of new discoveries and studies in their own field, to make them aware of events and developments in associated fields, and to provide students and newcomers the basic tools with which to learn fundamental and applied aspects of mass spectrometry.