Study of Red Algae (Eucheuma denticulatum (Burman) Collins et Harvey) Extract Bioactive Compounds using Liquid Chromatography Mass Spectroscopy - Mass Spectroscopy

Q3 Pharmacology, Toxicology and Pharmaceutics

Research Journal of Pharmacy and Technology Pub Date : 2024-01-19 DOI:10.52711/0974-360x.2024.00056

Syamsuri Syakri, Sartini Sartini, Upik A. Miskad, A. Aminuddin

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Abstract

Research has been carried out on the Study of Red Algae (Eucheuma denticulatum (Burman) Collins et Harvey) Extract Bioactive Compounds Using Liquid Chromatography Mass-Mass Spectroscopy (LCMS-MS). This study aims to determine the bioactive compounds produced in this red algae extract by means kinetic maceration of extraction. Reading of bioactive compounds using LCMS-MS to obtain compound results, compound structures, and molecular weights. The results show that there are 22 bioactive compounds contained in this plant. Consist of : 4-Dodecylbenzenesulfonic acid, NP-009092, 6-Hydroxycaproic acid, Xanthine, 3-Phenyilactic acid, Azelaic acid, Apro barbital, Decosahexaenoic acid, Methil hydrogen Phenylphoshonate, (1S)-1-Carboxy-N,N,N-trimethyl-2-(2-thioxo-2,3-dihydro-1H-imidazol-4-yl)ethanaminium, D-(+)-Tryptophan, uracil, ?17-6-keto Prostaglandin F1, Hypoxanthine, 20-hydroxy Prostaglandin F2?, 2-Hydroxy-4-methylthiobutanoic acid, N-(2-Furylmethyl)-3-[(2S,5aS,8aR)-1-methyl-5-oxodecahydropyrrolo[3,2-E][1,4]diazepin-2-yl]propanamide, 6-Hydroxycaproic acid, Methaphenilene, 15(S)-HpEPE, [(4Z)-5-(Methylsulfanyl)-4-penten-2-yn-1-yl]benzene, Suberic acid.

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利用液相色谱质谱法研究红藻（Eucheuma denticulatum (Burman) Collins et Harvey）提取物中的生物活性化合物 - 质谱法

利用液相色谱-质谱法（LCMS-MS）对红藻（Eucheuma denticulatum (Burman) Collins et Harvey）提取物中的生物活性化合物进行了研究。本研究旨在通过动力学浸提法确定红藻提取物中产生的生物活性化合物。利用 LCMS-MS 阅读生物活性化合物，以获得化合物结果、化合物结构和分子量。结果表明，这种植物中含有 22 种生物活性化合物。包括：4-Dodecylbenzenesulfonic acid、NP-009092、6-羟基己酸、黄嘌呤、3-苯基乳酸、壬二酸、Apro barbital、十碳六烯酸、苯磺酸甲酯、(1S)-1-羧基-N,N,N-三甲基-2-(2-硫酮-2,3-二氢-1H-咪唑-4-基)乙铵、D-(+)-色氨酸、尿嘧啶、?17-6-酮前列腺素 F1、次黄嘌呤、20-羟基前列腺素 F2？2-羟基-4-甲硫基丁酸，N-(2-呋喃甲基)-3-[(2S,5aS,8aR)-1-甲基-5-氧代十氢吡咯并[3,2-E][1,4]二氮杂卓-2-基]丙酰胺、6-羟基己酸、甲苯胺、15(S)-HpEPE、[(4Z)-5-(甲硫基)-4-戊烯-2-炔-1-基]苯、辛二酸。

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来源期刊

Research Journal of Pharmacy and Technology Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (miscellaneous)

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Research Journal of Pharmacy and Technology (RJPT) is an international, peer-reviewed, multidisciplinary journal, devoted to pharmaceutical sciences. The aim of RJPT is to increase the impact of pharmaceutical research both in academia and industry, with strong emphasis on quality and originality. RJPT publishes Original Research Articles, Short Communications, Review Articles in all areas of pharmaceutical sciences from the discovery of a drug up to clinical evaluation. Topics covered are: Pharmaceutics and Pharmacokinetics; Pharmaceutical chemistry including medicinal and analytical chemistry; Pharmacognosy including herbal products standardization and Phytochemistry; Pharmacology: Allied sciences including drug regulatory affairs, Pharmaceutical Marketing, Pharmaceutical Microbiology, Pharmaceutical biochemistry, Pharmaceutical Education and Hospital Pharmacy.