ANTI-ACNE FACIAL WASH FORMULATION FROM RED BETEL LEAF EXTRACT (PIPER CROCATUM RUIZ & PAV)

Siti Hindun, A. M. Gazzali, A. Najihudin, Siva Hamdani, Nopi Rantika, Winanda Nur Azizah
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Abstract

Acne can be caused by dust, sweat, and dirt that stick to the skin, forming blackheads. When blackheads become infected with bacteria, inflammation can occur. Therefore, it is essential to maintain good skin hygiene. One way to do this is by using natural ingredients with antibacterial properties. Red betel leaf is known to have antibacterial activity. This study aims to create a facial wash using red betel leaf extract that exhibits antibacterial properties against Propionibacterium acnes. The red betel leaf was extracted using the maceration method. Antibacterial testing was conducted against Propionibacterium acnes bacteria using the suitable diffusion method with a combination of red betel leaf extract at 10%, 15%, and 20%. The study found that facial wash products containing extract concentrations of 10%, 15%, and 20% demonstrated good physical stability, meeting the requirements of SNI-19-4380-1996 for pH, viscosity, specific gravity, and foam height. Additionally, the products showed potent antibacterial activity against Propionibacterium acnes bacteria, with inhibition zones of 29.0 mm, 32.6 mm, and 35.3 mm for the 10%, 15%, and 20% concentrations, respectively.
红槟榔叶提取物(Piper Crocatum ruiz & pav)抗痤疮洗面奶配方
粉刺可能是由于灰尘、汗液和污垢附着在皮肤上,形成黑头。当黑头受到细菌感染时,就会出现炎症。因此,保持良好的皮肤卫生至关重要。其中一个方法就是使用具有抗菌特性的天然成分。众所周知,红槟榔叶具有抗菌活性。本研究旨在使用红槟榔叶提取物制作一种洗面奶,这种洗面奶对痤疮丙酸杆菌具有抗菌特性。红槟榔叶采用浸渍法提取。使用合适的扩散法,结合 10%、15% 和 20% 的红槟榔叶提取物,对痤疮丙酸杆菌进行了抗菌测试。研究发现,提取物浓度为 10%、15% 和 20% 的洗面奶产品具有良好的物理稳定性,符合 SNI-19-4380-1996 对 pH 值、粘度、比重和泡沫高度的要求。此外,这些产品对痤疮丙酸杆菌具有很强的抗菌活性,10%、15% 和 20% 浓度的抑菌区分别为 29.0 毫米、32.6 毫米和 35.3 毫米。
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