Periodontal ligament and bone marrow derived stem cells in periodontal regeneration – A systematic review

IF 0.4 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
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引用次数: 0

Abstract

Background

Periodontal therapy aims to slow the progression of periodontal disease and encourage regeneration. Clinically, a number of periodontal therapies are used to treat periodontitis. Stem cell-based tissue regeneration is currently thought to be a promising therapeutic approach for periodontal tissue regeneration.

Objective

The systemic review's objective is to assess and compare the efficacy of periodontal ligament derived stem cells and bone marrow-derived stem cells in periodontal regeneration.

Methods

The Preferred Reporting Items for Systematic Review recommendations will be followed while conducting a systematic review. The efficiency of bone marrowderived stem cells (BMSCs) and stem cells produced from periodontal ligaments (PDLSCs) in regenerating periodontal tissue will be assessed. From 2013 to 2023, search engines will be utilized to identify appropriate information from databases like PubMed, Web of Science, and Scopus in order to locate research studies on PDLSCs and BMSCs in periodontal regeneration. The newly created periodontal ligament (NPDL), newly formed cementum (NC), and newly produced alveolar bone (NB) will be the main outcomes.

Results

The research evaluating bone marrow-derived stem cells-based therapies and periodontal ligament-derived stem cell-based therapies for the regeneration of periodontal tissue will be identified, and their efficacy in terms of histologic markers will be compared.

Conclusion

The most popular and efficient stem cell types for regenerating periodontal tissue are those produced from bone marrow and periodontal ligaments. The research will aid in the eventual clinical application of stem cell research.

牙周韧带和骨髓干细胞在牙周再生中的应用--系统综述
背景牙周治疗的目的是减缓牙周病的进展,促进牙周再生。在临床上,有多种牙周疗法用于治疗牙周炎。本系统综述的目的是评估和比较牙周韧带衍生干细胞和骨髓衍生干细胞在牙周再生中的疗效。方法在进行系统综述时,将遵循《系统综述首选报告项目》的建议。将评估骨髓来源干细胞(BMSCs)和牙周韧带来源干细胞(PDLSCs)在牙周组织再生中的效率。从2013年到2023年,我们将利用搜索引擎从PubMed、Web of Science和Scopus等数据库中找出适当的信息,以便找到关于牙周再生中的PDLSCs和BMSCs的研究。结果将确定评估基于骨髓干细胞和基于牙周韧带干细胞的牙周组织再生疗法的研究,并比较它们在组织学标记方面的疗效。结论 从骨髓和牙周韧带中提取的干细胞是再生牙周组织最常用、最有效的干细胞类型。这项研究将有助于干细胞研究的最终临床应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
129
审稿时长
83 days
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