A CASE REPORT ON STAGE IV HODGKIN'S LYMPHOMA

Keshavini S, Jagadeeshwari M, K. Dhivya
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Abstract

Hodgkin's lymphoma (HL) is a type of cancer in young adults,characterized by a large inflammatory microenvironment and a low number of malignant cells originating from B lymphocytes. It is a distinct lymphomatous cancer that is histologically defined by Reed-Sternberg cells in the right kind of cell environment.The disease primarily affects young adults, with a peak incidence occurring between the ages of 15 and 35. There are two subtypes: classical Hodgkin lymphoma (CHL) and nodular lymphocyte predominant HL (NLPHL). A 75-year-old patient with Stage IV HL was admitted for chemotherapy cycle IA (75% dose) on 14/06/2023 and was prescribed medications such as Adriamycin, Vinblastine, and Dacarbazine. The patient had systemic hypertension, a cataract, and a hernia. The patient also had a history of loss of appetite, neck swelling, and difficulty in hearing.A biopsy from level III right neck showed Hodgkin's lymphoma (Lymphocyte rich CHL).The next cycle of chemotherapy was scheduled on 28/06/2023.The patient was also admitted for cycle IIA chemotherapy (75% dose) and was prescribed the same medications again.The next cycle was scheduled on 26/07/2023.
霍奇金淋巴瘤 IV 期病例报告
霍奇金淋巴瘤(HL)是青壮年癌症的一种,其特点是炎症微环境大,B 淋巴细胞恶性细胞数量少。它是一种独特的淋巴瘤性癌症,在组织学上由处于适当细胞环境中的里德-斯滕伯格细胞所定义。这种疾病主要影响年轻成年人,发病高峰出现在 15 至 35 岁之间。该病有两种亚型:典型霍奇金淋巴瘤(CHL)和结节性淋巴细胞占优势的霍奇金淋巴瘤(NLPHL)。一名 75 岁的 IV 期 HL 患者于 2023 年 6 月 14 日入院接受 IA 周期化疗(75% 剂量),处方药物包括阿霉素、长春新碱和达卡巴嗪。患者患有全身性高血压、白内障和疝气。患者还有食欲不振、颈部肿胀和听力困难的病史。右颈部 III 级活检显示为霍奇金淋巴瘤(富含淋巴细胞的 CHL)。
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