Metal Induced Oxidative Stress in Fishes: A Review

Jugendra Nath Das, Satabdi Saikia
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Abstract

Fishes when exposed to various contaminants, particularly metals in their habitat can induce oxidative stress. In fishes, metals contamination results in oxidative stress by promoting reactive oxygen species (ROS) formation through redox cycling and impairing antioxidant defenses. ROS are harmful to all forms of aquatic life and can damage tissues and cellular components.Higher amount ofROS lead to varying degree of oxidative damage to the fish tissues including lipid peroxidation, protein and DNA oxidation as well as enzyme inactivation through different mechanisms as observed in different fish species. The present comprehension of how metals contribute to the onset of oxidative stress in fish is summed up in this review.
鱼类的金属诱导氧化应激:综述
鱼类接触到各种污染物,特别是栖息地中的金属时,会诱发氧化应激。在鱼类体内,金属污染会通过氧化还原循环促进活性氧(ROS)的形成,并损害抗氧化防御系统,从而导致氧化应激。ROS对所有形式的水生生物都是有害的,会破坏组织和细胞成分。ROS含量越高,对鱼类组织造成的氧化损伤程度就越大,包括脂质过氧化、蛋白质和DNA氧化以及酶失活。本综述总结了目前对金属如何导致鱼类氧化应激的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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