Hoang Le Tuan Anh, Ngo Viet Duc, Pham Van Cong, Ngo Van Hieu, Nguyen Van Dan, Vu Thi Trang, Do Thi Thu Hien, D. T. Tuan, Le Tuan Anh, Jeong Ah Kim
{"title":"Chemical constituents of Panax ginseng sprouts cultivated in Vietnam","authors":"Hoang Le Tuan Anh, Ngo Viet Duc, Pham Van Cong, Ngo Van Hieu, Nguyen Van Dan, Vu Thi Trang, Do Thi Thu Hien, D. T. Tuan, Le Tuan Anh, Jeong Ah Kim","doi":"10.1002/vjch.202300181","DOIUrl":null,"url":null,"abstract":"Eight compounds, including 20(R)‐ginsenoside Rg3 (1), Ginsenoside Rd (2), ginsenosides Rg2 (3), ginsenosides Re (4), β‐sitosterol (5), daucosterol (6), stigmasterol (7), and stigmasterol‐3‐O‐β‐glucoside (8) were isolated from the Panax ginseng sprouts cultivated in Vietnam. Their structures were elucidated by 1H, 13C NMR, and MS spectroscopic techniques and compared with the previous publication. In addition, their inhibitory activity on NO production and cytotoxic effects against human embryonic kidney cells (HEK‐293A) and human hepatocellular carcinoma (HepG2) were evaluated. This is the first study of the phytochemical investigation of P. ginseng sprouts cultivated in Vietnam and ginseng sprouts also contained the same main active ginsenosides as in the 4–6‐year old roots.","PeriodicalId":23525,"journal":{"name":"Vietnam Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vietnam Journal of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/vjch.202300181","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Eight compounds, including 20(R)‐ginsenoside Rg3 (1), Ginsenoside Rd (2), ginsenosides Rg2 (3), ginsenosides Re (4), β‐sitosterol (5), daucosterol (6), stigmasterol (7), and stigmasterol‐3‐O‐β‐glucoside (8) were isolated from the Panax ginseng sprouts cultivated in Vietnam. Their structures were elucidated by 1H, 13C NMR, and MS spectroscopic techniques and compared with the previous publication. In addition, their inhibitory activity on NO production and cytotoxic effects against human embryonic kidney cells (HEK‐293A) and human hepatocellular carcinoma (HepG2) were evaluated. This is the first study of the phytochemical investigation of P. ginseng sprouts cultivated in Vietnam and ginseng sprouts also contained the same main active ginsenosides as in the 4–6‐year old roots.
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