Nanomedicine-Based Drug Delivery Systems and the Treatment of Autism Spectrum Disorders: A Review

Micro Pub Date : 2024-02-27 DOI:10.3390/micro4010009
Zaria Jean-Baptiste, Yashwant Pathak, Kevin B. Sneed
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Abstract

Nanotechnology has played a pioneering role in advancing medical applications, aiming to enhance healthcare through innovation and collaboration. Nanomedicine can be seen expanding into many fields from cancer therapies, cosmetics, tissue regeneration, biosensing, and infectious diseases, and now, it is seen venturing into the realm of research geared toward autism spectrum disorder (ASD). ASD is a neurodevelopmental disorder characterized by restrictive, monotonous activities or fixed interests as well as difficulties with social communication. As of now, there are no validated quantitative metrics for diagnosing autism, nor is there a drug that is specifically designed to treat the condition. As identifiers of ASD have improved, the diagnosis of individuals who meet established criteria have dramatically increased over the years. Although there is still no recognized nanomedicine treatment specifically intended for ASD, research is looking into how nanotechnology might be used in a number of ASD-related areas. This comprehensive review examines prior research efforts aimed at preventing, treating, and diagnosing individuals with ASD. It particularly focuses on the significance of prenatal care and investigates advancements in drug delivery methods through the blood–brain barrier concerning ASD treatment and management.
基于纳米药物的给药系统与自闭症谱系障碍的治疗:综述
纳米技术在推动医疗应用方面发挥了先驱作用,旨在通过创新与合作提高医疗保健水平。纳米医学已扩展到癌症治疗、化妆品、组织再生、生物传感和传染病等多个领域,现在,它又开始涉足针对自闭症谱系障碍(ASD)的研究领域。自闭症谱系障碍是一种神经发育障碍,其特点是活动受限、单调或兴趣固定,以及社交沟通困难。到目前为止,还没有有效的量化指标来诊断自闭症,也没有专门治疗自闭症的药物。随着自闭症鉴定方法的改进,这些年来符合既定标准的诊断率大幅提高。虽然目前还没有公认的专门针对 ASD 的纳米医学治疗方法,但研究人员正在探索如何将纳米技术用于 ASD 的多个相关领域。本综述对之前旨在预防、治疗和诊断 ASD 患者的研究工作进行了审查。它特别关注产前护理的重要性,并研究了与 ASD 治疗和管理有关的通过血脑屏障给药方法的进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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