Ghafis (Agrimonia eupatoria): An In-depth Review of its Historical Context, Therapeutic properties, Ethnopharmacological applications, and Scientific research

Abstract

Agrimonia eupatoria, commonly known as Ghafis, holds a significant role in traditional herbal medicine across different regions. This perennial plant, part of the Rosaceae family, has been used in Unani medicine for its various healing properties since ancient times. Ghafis is known for its abilities as a demulcent, stomachic, blood purifier, diuretic, emmenagogue, anti-inflammatory, and astringent agent. Traditionally, it has been employed to treat liver and spleen inflammation, fevers, ulcers, jaundice, wounds, and gastrointestinal disorders. Ethnopharmacological practices have also recognized its antioxidant, antimicrobial, and diuretic effects. Recent scientific studies have further explored its potential in managing diabetes, neuropathic pain, oxidative stress-related disorders, and protecting the liver. This review aims to provide an overview of Ghafis, covering its description, habitat, traditional uses, and recent scientific studies. Ghafis emerges as a valuable herbal remedy with ongoing relevance in herbal medicine and Unani pharmacotherapy. Keywords: Ghafis, Agrimonia eupatoria, Agrimony, Unani Medicine